PubMed Health⌕ Search

Biomedical subjects

J Makhoul

Publications and source records attributed to J Makhoul.

6 recordsLinked to original sources
PubMed2002

[Optic neuropathy in Strumpell-Lorrain disease: presentation of a clinical case and literature review].

This report describes a 36-year-old female with bilateral optic atrophy. Physical examination was normal except for subclinical signs of lower limbs spasticity. Her father was affected of Strumpell-Lorrain disease. The clinical characteristics of Hereditary Spastic Paraplegia or Strumpell-Lorrain disease are: progressive spasticity of the lower limbs and pathological reflexes. Pathologically, this disease is characterized by a degeneration or demyelinization of the cortico-spinal system and, to a lesser extent, of the posterior cord and the spino-cerebellar system. Optic neuropathy and dyschromatopsy have already been reported in a small group of patients. Visual acuity ranged from 20/20 to 20/200. Visual field alterations consisted of superior bitemporal amputation. Fundus examination showed optic atrophy. The incidence of optic neuropathy in Strumpell-Lorrain disease is quite high but its presence is often overlooked. Most patients are asymptomatic, but signs of optic nerve dysfunction are evident at clinical examination. According to some authors, there is an inverse relationship between the impairment of walking and the visual dysfunction. This was also noted in our case.

Adult↗
PubMed1995

State of the art in continuous speech recognition.

In the past decade, tremendous advances in the state of the art of automatic speech recognition by machine have taken place. A reduction in the word error rate by more than a factor of 5 and an increase in recognition speeds by several orders of magnitude (brought about by a combination of faster recognition search algorithms and more powerful computers), have combined to make high-accuracy, speaker-independent, continuous speech recognition for large vocabularies possible in real time, on off-the-shelf workstations, without the aid of special hardware. These advances promise to make speech recognition technology readily available to the general public. This paper focuses on the speech recognition advances made through better speech modeling techniques, chiefly through more accurate mathematical modeling of speech sounds.

Algorithms↗
PubMed1991

[Performance of routine Doppler studies for screening of the fetus in de uterus in the 3d trimester of pregnancy].

We did screening Doppler investigations of the foetus circulation during the third trimester of pregnancy, and established reference curves for Resistance and Pulsatility Indexes of the umbilical and middle cerebral as well as for the ratios of these indexes. We compared these indexes in groups of fetuses with different characteristics at birth. It turned out that low birth-weight, or the presence of dips in the fetal heart rate during labor is associated with some distinctive anomalies of the measured indexes compared with the control group with a normal birth-weight and no deceleration during labor.

Adult↗