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Biomedical subjects

J Malinowski

Publications and source records attributed to J Malinowski.

At least 37 records · Page 2Linked to original sources
PubMed1984

The induction of oxazolone-specific T suppressor afferent cells in mice by hapten-modified isologous IgG.

Injection of isologous 4(ethoxymethylene)-2-phenyl-oxazolin-5-one (oxazolone; OX)-substituted thymocytes or OX-labeled IgG (OX-IgG) into mice produces specific unresponsiveness in which immunization with homologous (OX), but not heterologous (picryl chloride), hapten on the skin does not result in significant contact sensitization. However, while injection of OX-substituted thymocytes triggers suppressor cells which inhibit the effector stage of contact sensitivity reaction, OX-IgG induces cells which suppress exclusively the afferent stage of reaction. In contrast to OX-IgG, OX-substituted F(ab')2 fragments, IgM, and albumin are ineffective. T suppressor afferent cells have Ly-2 and I-J surface markers and their precursors are resistant to cyclophosphamide treatment and adult thymectomy. We assume that T suppressor afferent cells recognize antigen in conjunction with intact IgG molecules, although the exact mechanism is unclear.

Animals↗
PubMed1982

Serum antipapain activity during normal pregnancy.

Antitryptic, antichymotryptic and antipapain activities in maternal serum were measured in the course of normal pregnancy. An increase in inhibitory capacity toward the three examined proteases was demonstrated. The level of antipapain activity was highest between the 13th and 24th weeks of gestation in contrast to antitrypsin and antichymotrypsin activities which have shown the highest values between the 25th and 36th weeks of pregnancy.

Chymotrypsin↗
PubMed1977

[Free autologous skin implantations in plastic periodontal surgery].

From 1972 to 1974, 25 autologous skin transplantations were carried out within the framework of complex periodontal therapy. Prior to the operation, ischemia and mobility of the marginal gingiva were found in all patients in the region of the lower incisors. After the operation, the gingiva had broadened by 5.6 to 6.6 mm. The grafts shrank after the operation. In two cases the graft failed and was rejected. The transplanted skin does not change in color, although keratinization of the transplanted skin is considerably reduced.

Adolescent↗