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Biomedical subjects

J Marín Martín

Publications and source records attributed to J Marín Martín.

10 recordsLinked to original sources
PubMed2000

[Spontaneous retroperitoneal hematoma secondary to the rupture of suprarenal myelolipoma].

OBJECTIVE: To describe a case of adrenal myelolipoma in a patient that presented with retroperitoneal hemorrhage. METHODS/RESULTS: A 53-year-old patient that presented with retroperitoneal hemorrhage is described. A CT scan showed a 14 cm fat-containing mass in the right adrenal area surrounded by another hyperdense mass suggestive of hemorrhage. A right adrenalectomy was performed. Histopathologic analysis of the mass confirmed the clinical diagnosis of ruptured adrenal myelolipoma. The clinical and therapeutic aspects are discussed and the literature is briefly reviewed. CONCLUSIONS: Adrenal myelolipomas are rare benign lesions and are usually asymptomatic. Spontaneous rupture is very uncommon and is related with the size of the tumor. To our knowledge, only six cases have been previously reported in the literature.

Adrenal Gland Neoplasms↗
PubMed1999

[Relapse in brucella orchiepididymitis].

This paper describes a case of systemic brucellosis accompanied by brucellar orchitis that resolved favourably. There was however a relapse at the testicular level inappropriately treated that triggered a new episode of systemic brucellosis.

Adult↗
PubMed1999

[Squamous carcinoma of the male urethra, its presentation as a scrotal abscess].

OBJECTIVE: To report a case of urethral carcinoma presenting as scrotal abscess. METHODS: A 53-year-old man presented with swelling, redness and pain in the scrotum. He had a history of urethral stricture and multiple scrotal abscesses. Incision and drainage were performed and the patient was treated with antibiotics without improvement. Incision and drainage were repeated and a biopsy of the tissue edges of the abscess were performed. RESULTS: Histopathological analysis disclosed a squamous cell carcinoma arising from the urethra. CONCLUSION: Patients with a history of urethral stricture should be followed closely. A scrotal biopsy should be performed in patients who do not improve with antibiotic therapy.

Abscess↗
PubMed1996

[P53 protein gene. Review of the literature and assessment of the prognostic impact of its mutations in bladder tumors].

The p53 protein, of the core protein group, was initially considered an oncogene but it was later noted to be included in the group of tumour-suppressive genes, the function of which seems to be focused in the control of cell growth, regulation of DNA transcription, and inhibition of certain oncogenes. A mutant protein variety has been observed with longer than normal mean life and altered function, so that it is not effective for the inhibitory control of cell growth. Mutations of that protein's gene, located in the short arm of chromosome 17, have been discovered in a large variety of tumours in humans, and in the urogenital region they have been consistently seen in both vesical and prostate tumours. The objective of the study was to confirm the need of this gene mutation, so that the vesical transitional cell tumour develops an infiltrant nature. The presence of mutations in this gene's exons 5 and 8 in infiltrant transitional cell tumours (28.5% cases) was demonstrated using as controls either surface transitional cell tumours, non-transitional tumours and healthy vesical tissue obtained together with the tumour specimen in each surgical procedure. The methods used were PCR (polymerase chain reaction) and the identification of the mutated specimen through TGGE (temperature gradient electrophoresis). The absence of mutations in the control strips together with the observation of mutations in the specimens from infiltrant tumours confirms the above hypothesis.

Genes, p53↗
PubMed1996

[Pyonephrosis caused by torulosis glabrata].

Fungal urinary infections are becoming increasingly frequent as a result of widespread use of broad spectrum antibiotics, an increased number of immunocompromised patients and the greater longevity of chronic patients. Urinary tract infections by Toruplosis glabrata only come second in frequency after those caused by Candida albicans, accounting for 5 to 25% of all infections caused by fungi. The paper presents one case of pyonephrosis by Toruplosis glabrata in a female patient treated with fluconazole who later underwent nephrectomy. A description is made of the clinical picture, diagnosis and treatment of these infections.

Cryptococcosis↗