Biomedical subjects

J Martínez Vidal

Publications and source records attributed to J Martínez Vidal.

At least 19 recordsLinked to original sources

PubMed2006

[Supraglottic laryngectomy. Still on-going].

INTRODUCTION: Horizontal supraglottic laryngectomy (HSL) allows the preservation of a functioning larynx and avoids a permanent tracheostoma. Its use and training have been conditioned by the employment of organ preservation programs and endoscopic laser surgery. OBJECTIVE: To show functional and oncological long-term results of HSL. MATERIAL AND METHOD: 110 patients treated with HSL with a minimum of 5 years follow-up. RESULTS: Local control, 89% for T1, 91% for T2, 80% for T3 and 91% for T4. Regional control 80.9%. Cause specific survival, 77.6%, 72.6% and 67% at 3, 5 and 10 years, significantly influenced by N-stage. Functional larynx preservation, 87%, with a 8.5% of non-decanulated patients. CONCLUSION: HSL is a safe surgical procedure, with similar functional and oncological results to other therapeutic options. Its indications should be considered according to own experience and results.

Adult↗

PubMed2000

[Second primary tumors in patients with carcinoma of the head and neck].

With improved loco-regional control of cancer of the head and neck, second primary tumors (SPT) have an increasingly negative impact on survival. The appearance of SPT depends on the location and extension of the primary and is associated with lower survival. SPT were studied in a series of 1493 previously untreated patients with carcinoma of the head and neck and a minimum follow-up of 2 years. SPT occurred in 6.3% (96/1493). SPT were associated with the following primary tumor sites: 10.8% (57/727) larynx, 4% (6/153) hypopharynx, 4% (16/404) oral cavity, and 4% (6/153) oropharynx. Forty-three percent (42.7%) of SPT were carcinomas of the head and neck, 27% bronchogenic carcinomas, and 17.7% esophageal carcinomas. Survival at 6 months, 1 year, 3 years, and 5 years of patients diagnosed as SPT was 62%, 43%, 21%, and 16%, respectively.

Adult↗

PubMed2000

[Non-Hodgkin's lymphoma of the parotid gland: 2 cases].

We report two cases of bilateral parotid swelling at initial clinical assessment of non-Hodgkin lymphoma. The swelling was not associated with other symptoms. They both were stage IV and were treated by chemotherapy. We have reviewed the literature about first manifestations of the disease, clinical diagnosis and incidence. The importance of early biopsy of such lesions is emphasised.

Female↗

PubMed1999

Use of the cross-section technique linked with multivariate calibration methods to resolve complex pesticide mixtures.

The potential of the cross-section (CS) approach in combination with the partial least squares (PLS) and principal component regression (PCR) was assessed in the resolution of a complex pesticide mixture showing twelve overlapped components in High Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD). Careful selection of the CS through the three-dimensional (3D) (A, lambda, t) data matrix gave two-dimensional (2D) signals with the best sensitivity for the determination of each pesticide. In all cases, the application of the PLS method demonstrated a better quantitative prediction ability than that of the PCR method. The CS-PLS approach is a powerful analytical tool. Ten pesticides were well-resolved, while for the other two pesticides of the mixture prediction ability was poor, and they could not be determined, probably due to their low net analytical signal. The CS-PLS model was evaluated by predicting the concentrations of independent test set samples. Finally, the proposed model was successfully applied for the determination of these pesticides in groundwater.

Calibration↗

PubMed1999

[Supraglottic laryngectomy: 3-year and 5-year results].

A series of 84 patients who underwent horizontal supraglottic laryngectomy between 1980 and 1995 were analyzed. All patients were men, mean age 56 years. Neck metastases were found in 37 patients; 17 patients had stage I disease, 22 stage II, 13 stage III and 32 stage IV. One patient died in the postoperative period. Pharyngocutaneous fistula was the most frequent complication, being present in 10.7% of patients. The 3-year and 5-year survival rates were 78.9 and 74.2%, respectively. Local control was 91.6% at 3-years and 90.4% at 5-years. Local recurrences occurred in 6 patients, all of whom were salvaged by total laryngectomy and radiotherapy. Neck failure occurred in 15 patients, 2 of who were salvaged with further treatment. Second primary tumors appeared in 10 patients, 30% in the head and neck, after a mean interval of 77 months.

Adult↗

PubMed1997

[Recurrence of peritracheostoma and emergency tracheotomy].

The relationship between emergency tracheotomy (ET) and stomal recurrence (SR) was evaluated in 369 patients who underwent surgery for laryngeal cancer. Emergency tracheostomy was performed in 31 patients. Age, sex, primary location, T stage, pN stage, histological grading, and time from emergency tracheotomy to definitive treatment were examined. Stomal recurrence occurred in 2.1% overall; in 1.2% of the tracheotomy-free group, and in 13% (4/31) of the emergency tracheotomy group (p < 0.0001). Recurrences were significantly more frequent in subglottic (p = 0.00007) and T3 lesions (p < 0.0001). Emergency tracheostomy often is needed in patients who have primary subglottic tumors or tumors than invade the subglottis. The relationship between ET and SR appears to be more circumstantial than causal. Aggressive local treatment is recommended in patients with subglottic lesions or subglottic tumor extension to prevent SR.

Adult↗

PubMed1996

[Sjogren syndrome: clinics and ENT diagnosis].

Prospective study covering 38 cases of Sjögren's syndrome (S.S.) diagnosed after early clinical suspicion awaken for xerostomy and xerophtalmy, once excluded those cases which pathology was previously known. Thirty-two cases pertaining to primary malady (P.S.S.) being secondary (S.S.S.) the others. The clinical E.N.T.-symptomatology stand out in our series, because the throat dryness and taste and olfactory alterations. The 53 percent of patients have consulted with other specialists without actualizing the diagnosis. The AA. discuss complementary diagnostic methods (Schirmer's test, rose bengal stain, sialometry, auto-antibodies and biopsy of minor salivary glands) and diagnostic criteria, and fix the otolaryngologist role in the management of these patients.

Adult↗

PubMed1995

[Diagnosis and surgical treatment of pharyngeal space tumors].

The AA. present a retrospective study regarding their experience, in the last 20 years (1973-1993), on diagnosis and management of tumors localized in the parapharyngeal space. In this interval 16 patients, carrying on 17 parapharyngeal tumors, were diagnosed. The incidence was similar in both sexes, the ages ranging widely, the clinic inspecific and the diagnosis confirmed late. They advise the CT with opaque media, nowadays associated to NMR, as suitable diagnostic routine. Fine needle biopsy is not recommended as regular procedure. The great deal of cases carried benign tumors, though individually metastatic epidermoid carcinomas were the most prevalent, followed by salivary and neurogenic growths. 15 individuals underwent surgery. In all but one the cervical approach without mandibulotomy--supposed to be the selective procedure--was done. No one was tracheotomized. Four postoperative nervous complications presented: 2 corresponding to malingnancies. Neither major complications nor perioperative mortality resulted.

Adolescent↗

PubMed1994

[ENT diagnosis of Wegener's syndrome].

In spite of its rarity Wegener's granulomatosis is of great concern to be otolaryngologist because the malady may start in the territory of the speciality, challenging the actual diagnosis, owing to the inespecificity of the symptomatology, to its torpid evolution, as well as the potential harmfullness of process. This paper inform of the retrospective study done by the AA. in the last ten years, about 4 cases diagnosed and treated by them. All the possible diagnostic measures are contemplated: clinical and histopathological findings and the newly introduced tests for anticytoplasmatic antibodies against the neutrophiles. A review of the bibliography on the subject is adjoined. All the considered patients consulted at the beginning with the otolaryngologist. Diagnostic suspicion aroused only in patients with nasal complaints (50 percent) and were not under suspicion those with ear symptoms. Positive diagnosis were confirmed in all cases through renal biopsies. Nasal biopsies resulted negatives. When the syndrome started in low aged patients the evolutive course showed deleterious and the affected died after a short term of few months. In more aged a survival of 8-9 yeas was reached.

Adolescent↗

PubMed1993

[Foreign bodies in ENT analysis after one year's assistance].

Foreign bodies sitting in the E.N.T.-area are the most urgencies needing immediate attention by the specialist. The AA. study the 738 cases admitted at their Department, for correlative consultations, in one year-term, because of suspicion of accidental lodgements. They arrange the whole lot in 5 not specific localizations, with the aim of consider the peculiarities of each group. In the great deal of instances the patients were worried for oropharyngeal penetration, followed by a lower number complaining of oesophageal distress. Considerations regarding the usefulness of ancillary exploratory techniques, specially the Radiology.

Adolescent↗

PubMed1979