Biomedical subjects

J Mastrobattista

Publications and source records attributed to J Mastrobattista.

3 recordsLinked to original sources

PubMed1996

Recurrent hyperthyroidism in consecutive pregnancies characterized by hyperemesis.

A 34-year-old Caucasian woman was seen and evaluated for hyperemesis and abnormal thyroid function tests, consistent with hyperthyroidism, during her second pregnancy. Her hyperemesis and hyperthyroidism both resolved during the second trimester of this pregnancy. She recounted very similar symptoms of similar duration in her first pregnancy. She was again monitored in a third pregnancy during which hyperemesis and hyperthyroidism were once more documented, resolving during the second trimester. The recurrence of hyperemesis in three consecutive singleton pregnancies, with documentation of transient hyperthyroidism in two of these pregnancies, is suggestive of human chorionic gonadotropin (hCG)-mediated hyperthyroidism. Either the trophoblasts synthesized hCG of high thyrotropic grade or, alternatively, hCG could be modified in the maternal tissues, resulting in molecules with greater thyrotropic activity. These potential mechanisms are discussed.

Adult↗

PubMed1994

Subconjunctival THC:YAG laser sclerostomy under a partial-thickness corneal flap.

To evaluate the safety and effectiveness of THC:YAG laser sclerostomy in reducing intraocular pressure (IOP), we performed 16 subconjunctival sclerostomies under a partial-thickness corneal flap. We report the 3- and 6-month follow-up results in these patients, all of whom had intractable glaucoma resistant to previous surgical treatment. The mean IOP decreased from a pretreatment value of 30 mm Hg to a posttreatment value of 14 mm Hg at 3 months. Fifty-seven percent of the treated eyes achieved an IOP below 20 mm Hg at 6 months. A significant reduction in glaucoma medications is also reported among the successes. Complications were minimal.

Adult↗

PubMedDate not supplied

Subconjunctival THC:YAG laser sclerostomy under a partial thickness flap.

Holmium laser sclerostomy is a useful surgical procedure in eyes with refractory glaucoma. The success rate is 60%, comparable to the success rate with a seton, but there is a significantly lower rate of complications compared to a seton. Furthermore, the conjunctiva is minimally dissected and less surgical trauma is involved with the procedure, an advantage compared to other filtering operations. The use of a corneascleral flap producing a "guarded" Holmium sclerostomy reduces the incidence of complications and there were no flat or shallow anterior chambers in the 47 eyes operated on and reviewed in this study.

Adult↗