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Biomedical subjects

J Maurin

Publications and source records attributed to J Maurin.

At least 19 recordsLinked to original sources
PubMed1978

Does the nucleus raphes participate in the regulation of resting and stress-induced hypothalamic-pituitary-adrenocortical activity in the pigeon?

Extensive multiple electrolytic lesions were placed into the nucleus raphes of the brain stem in the pigeon. Diurnal pituitary-adrenocortical rhythmicity appeared not to be altered and basal plasma corticosterone level remained quite normal in raphe lesioned birds. Electrical stimulations through permanently implanted electrode were delivered in various central nervous structures in unanaesthetized, freely moving pigeons. Stimulations of nucleus raphes and of various parts of formatio reticularis led to a significant rise in plasma corticosterone within 16 to 19 min after the beginning of the stimulating session. Then, plasma B came again to initial level within 15 minutes. Stimulations of the corticotropic area of the hypothalamus (n. posterior medialis hypothalami) and of archistriatum dorsalis induced an early plasma corticosterone increase occurring immediately after the stimulating burst (10 min). Stimulating the n. septum medialis also had an immediate, but reverse (decrease) effect on plasma corticosterone level. Stress-induced pituitary-adrenal cortical activation exhibited a temporal pattern quite similar to that observed after brain stem (n. raphes or formatio reticularis) stimulation. It is suggested that these various limbic and brain stem areas might be involved in some "limbic system-midbrain circuit" with two components : The forebrain component might be involved in the regulation and diurnal modulation of basal hypothalamic-pituitary-adrenocortical function, the brain-stem component interferring with stress-induced responses.

Adrenal Cortex↗
PubMed1977

Sampling survey on brucellosis among farmers and their families in Ille-et-Vilaine (Brittany).

A three-stage sampling survey among farmers and their families living on farms in the department of Ille-et-Vilaine gave the following results: Among 490 persons examined 313 (64 per cent) showed a positive skin test and 105 (21 per cent) a positive serological reaction; 88 of the 105 patients ignored their health status, although 45 of these presented clinical symptoms (nine per cent). This survey is continuing in order to study the non-respondents and to better analyse the epidemiological situation at a farm level.

Adolescent↗
PubMed1977

[Raphe nucleus and corticorophic activity in pigeons].

Multiple electrolytic lesions were placed in the raphe area of pigeons. Basal plasma corticosterone level (B) was found not to be altered. Stress-induced adrenocortical activation was markedly reduced in raphe lesioned pigeons as compared to controls. Electrical stimulation of the nucleus raphes in permanently implanted, unrestrained and unanesthetized birds induced a significant rise in B. However the magnitude of the response to raphe stimulating was lower (1/2 approximately) and especially later than after hypothalamic stimulation since it paralleled exactly the pattern of stress induced activation.

Animals↗
PubMed1977

[Curable ECHO 5 virus encephalitis. Clinical, electroencephalographic, virologic and ultrastructural study].

A 10 1/2 years old boy fell brutally ill with a fit followed by confusion, and then by deep coma, with 40 degrees C fever and morbilliform rash. Consciousnesse came back within ten days, with transient Parkinson-like tremor. Myoclonus persisted for about six months. Complete recovery was followed up for six years. A diagnosis of encephalitis was considered on early EEG evidence (stereotyped repetitive sharp wave bursts) and was confirmed by isolation of ECHO 5 virus from brain specimen, and ultrastructural observation of characteristic cytopathic effect (disappearance of organelles, proliferation of smooth membranes) and of probable viral particules in astrocytes, without any inflammatory process.

Cerebral Cortex↗