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Biomedical subjects

J McQuillin

Publications and source records attributed to J McQuillin.

43 records · Page 3Linked to original sources
PubMed1968

Rapid diagnosis of herpesvirus hominis infections in superficial lesions by immunofluorescent antibody technics.

Scrapings from lesions of the skin and mucous membranes of 14 patients suspected of suffering from suspected Herpesvirus hominis infections were examined by both fluorescent antibody and routine isolation techniques. There was complete correlation between results by both methods in all 14 cases, 12 being positive. No positive fluorescence was obtained from scrapings of seven control patients with a variety of skin diseases. Thirteen patients with corneal lesions were similarly investigated. Of the 10 scrapings which showed positive fluorescence, nine were confirmed by virus isolation. It is suggested that as more antiviral agents become available the application of a fluorescent antibody technique for testing virus sensitivity in tissue culture could become a practical method.

Adolescent↗
PubMed1968

Application of immunofluorescent antibody technique in rapid diagnosis of respiratory syncytial virus infection.

Seventy-eight unselected children under the age of 2 years suffering from acute respiratory infections were investigated by the fluorescent antibody technique and a comparison was made with conventional isolation and serological methods. Sixty-nine per cent. of children with bronchiolitis were diagnosed as suffering from respiratory syncytial virus infection on the day of admission by examination of nasopharyngeal secretions. There were 44 children with respiratory syncytial virus infection diagnosed by conventional methods over a month, but by using fluorescent antibody techniques on tissue culture 53% were diagnosed by the second day, 71% by the fourth day, and 82% by the seventh day. The method of choice for a rapid diagnosis of respiratory syncytial virus infection is by examining nasopharyngeal secretions, when 90% of those with this infection can be diagnosed on the day of admission to hospital.

Animals↗