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Biomedical subjects

J Medrano

Publications and source records attributed to J Medrano.

At least 55 records · Page 3Linked to original sources
PubMed1979

[Results of 200 renal transplantations (author's transl)].

Two hundred renal transplantations were performed on 187 patients between July, 1972 and June, 1978. On a follow-up of 6--78 months the survival rate after allogenic transplantation was 80% at one year and 64% at five years. Satisfactory renal function was present in 62% at one year and 31% at six years. Gastrointestinal complications were common and caused about 40% of all deaths. Severe infections were the second most common cause of death. Local complications required explantation in 4%, and caused death in 0.5% of cases. Change in the treatment regimen, using less massive immunosuppressive measures during acute rejection, lowered the death-rate without a higher loss of transplants. The death-rate was 16% at three months and 26% at one year in the first of the 200 transplantations, but 6% and 12%, respectively, in the last 50 consecutive transplantations. The survival rate of patients with transplants is thus comparable to that of patients receiving chronic haemodialysis.

Azathioprine↗
PubMed1979

[Traumatic pancreatic pseudocysts in childhood (author's transl)].

Two children had extensive resection of the pancreas due to a posttraumatic pseudocyst. Function of the endocrine and exocrine pancreas was reinvestigated following surgery and found to be normal. Based upon these observations pathogenesis, clinical and therapeutical aspects of pancreatic pseudocysts in childhood are reviewed.

Blood Glucose↗
PubMed1978

[Peptic ulcer in children: diagnosis and treatment (author's transl)].

Within a period of 14 years 23 children were treated for peptic ulcer (0.039% of all inpatients). Acute ulcers were seen in neonates or after major surgery, and were diagnosed only after perforation or bleeding. Chronic ulcers predominantly occurred after the sixth year. In addition to abdominal pain and colic, perforation and haemorrhage were also seen, the latter occasionally without previous symptoms. Three children were operated on for perforation, two for gastroduodenal haemorrhage. One of them, a neonate, died of septicaemia with subarachnoid haemorrhage. The bleedings were stopped by purse-string suture, the perforations by oversewing in two, local excision in one. Follow-up examination was undertaken in 14 of the 22 surviving children six months to 12 years after the initial manifestation. None had a recurrence. It is concluded that peptic ulcer is more frequent in children than is generally supposed. Treatment is mainly conservative. In case of perforation or haemorrhage the least possible surgical intervention should be practised.

Adolescent↗
PubMed1976

[Spontaneous rupture of the allografted kidney (author's transl)].

Spontaneous rupture of allografted kidneys occurred in 6 cases after 95 renal transplantations performed in the Department of General Surgery at the University Clinic in Essen. An analysis of this complication after renal transplantation is presented considering our own experience and 60 cases from the literature. The characteristic symptoms which were found in all cases consisted of oliguria, pain and swelling of the graft site and signs of hemorrhage. In 90% transplant rupture occurred within 3 weeks postoperatively. The surgical therapy should preserve the ruptured organ whenever possible. In 5 of our 6 cases we were successful in preserving the graft by suturing the tear. The analysis of the etiologic factors of 66 cases shows that oedema of the renal graft is the most common finding. A possible etiological factor seems to be the method of organ preservation.

Adult↗
PubMed1975

[Blood-pressure behavior in rats following the diversion of renal-vein blood into the portal vein].

Experimental studies on 22 hypertonic rats which had previously one kidney removed show that the deviation of the renal vein blood into the portal vein through a cavorportal or splenoportal anastomosis does not result in a lowering of the experimentally induced renovascular hypertension. These anastomoses did not alter the blood pressure in 3 normotonic rats. The prophylactic use of these anastomoses could not prevent the development of experimental renal hypertension in 2 of 3 test animals.

Animals↗
PubMed1975

[The postoperative vomiting after pyloromyotomie (author's transl)].

Following pyloromyotomy vomiting may persist for several hours or days in a high percentage of children due to a loss of gastric tone. If this is the suspected cause the feedings must be adjusted individually. Other causes for postoperative vomiting are incomplete pyloromyotomy and surgical complications, associated anomalies of the gastrointestinal tract and nonsurgical diseases. A correct diagnosis can usually be made by the assessment of the beginning and the type of vomiting and the other symptoms. To shorten the period of hospitalization is advantageous for decreasing the occurrence of additional diseases.

Child↗