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Biomedical subjects

J Meier

Publications and source records attributed to J Meier.

170 records · Page 10Linked to original sources

Human brain: aldehyde dehydrogenase activity and isozyme distribution in different areas.

Three human post-mortem brains were dissected into seventeen areas and assayed for aldehyde dehydrogenase (EC 1.2.1.3) activity employing two assay systems: one at 68 microM and another at 13.6 mM propionaldehyde. The levels of activity with 68 microM propionaldehyde were significantly higher in cerebellum and putamen. The same brain areas were also examined by isoelectric focusing. By this procedure two distinct bands of aldehyde dehydrogenase activity (the cytoplasmic E1 and mitochondrial E2) could be readily visualized in cerebellum and putamen while other brain areas contained mainly the mitochondrial E2 isozyme.

Aged↗

[Whipple disease with negative duodenal histology--a case report and review of the literature].

The arthritis of Morbus Whipple is an early clinical manifestation of this rare disease. As the arthritis precedes the gastrointestinal symptoms, very often it is an important early diagnostic clue in this potentially fatal disease. The classical method in establishing the diagnosis is to show the characteristic histologic features in the affected tissues or in small bowel biopsy. Employed in the latter are usually multiple directed biopsies during duodenal endoscopy. This case report gives an example that the duodenum may be spared during active Whipple's disease and even affected tissues must not show the characteristic features of Morbus Whipple.

Biopsy↗

[AIDS--comparison of knowledge, attitude and behavior of Hannover and Leipzig medical students].

An investigation was carried out in students of the faculties of medicine at Hannover and Leipzig by handling a questionnaire on their knowledge, beliefs and attitudes on AIDS. The sample was 354 at Hannover and 365 at Leipzig consisting of students at the beginning of the first course on the one hand and at the end of studies on the other, both in 1990/91. In the two cities an acceptable knowledge was found of the basic generals of HIV-transmission. Differences appeared at the estimation on behalf of infection-risks by non detectable transmission ways. There is no worth mentioning difference in the students' knowledge between the first and the fifth academic year. On the contrary, uncertainties are stronger marked at the end of the courses than in the beginning. Students' attitudes are very similar in Hannover and Leipzig. Significant differences between Hannover and Leipzig are demonstrable especially on beliefs. Medical students in Leipzig tend sooner to be in favour for interventional measures by the public authorities, clearly visible by their advocating a wide use of HIV-test application to patients, clinic staff and other health professionals even against their will. The students in Hannover are more liberal in this point. Altogether the comparison between Hannover and Leipzig shows a lot of equalities. Existing differences may be on the way to disappear within the farther process of German unification.

Acquired Immunodeficiency Syndrome↗