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Biomedical subjects

J Mellan

Publications and source records attributed to J Mellan.

At least 19 recordsLinked to original sources
PubMed1991

Recidivous offence in sadistic homosexual pedophile with karyotype 48, XXXY after testicular pulpectomy. A case report.

The case of recidivous sexual offender with genetically caused mental retardation and primary hypogonadism (Klinefelter's syndrome with karyotype 48, XXXY) is described. He was examined after sadistic abuse of a boy aged 13 that he had committed 19 years after performed testicular pulpectomy. Plasmatic level of testosterone was found 4x higher than mean level in men after orchidectomy. Histological examination of residual scrotal tissues proved that the source of androgens were hyperplastic nodules of extratesticular Leydig cells.

Biopsy↗
PubMed1979

Klinefelter's syndrome: sexual development and activity.

Determination of plasma testosterone in 105 patients with Klinefelter's syndrome 16--45 years of age revealed that at each 5-year age interval values of male hormone were lower than in a control group of 25 normal adolescents and 85 fertile and potent men. Analysis of heterosexual development by means of the HTDM Questionnaire in 110 patients with Klinefelter's syndrome age 21--40 years, who were examined mainly for sterility and signs of imperfect somatosexual development, revealed a distinct retardation of sociosexual development compared to that of 325 normozoospermic men from sterile marriages. For eight out of 12 items on the HTDM Questionnaire the differences were statistically significant. Examination by means of the SAM Questionnaire in these two groups revealed that the sexual activity of examinees with Klinefelter's syndrome was significantly weaker than that of fertile and potent men. For 15 out of 18 items on the SAM Questionnaire the differences were statistically significant.

Adolescent↗
PubMed1979

Men with a distinct testicular hypoplasia: sexual development and activity.

In 101 married men examined for sterility a distinct testicular hypoplasia was found. The long axis of both sexual glands was shorter than 30 mm. Their heterosexual development and activity in sex life were studied by means of HTDM and SAM Questionnaires. A comparison with a group of 325 normozoospermic men of the same age has shown that the heterosexual development was in the pathological group only slightly retarded but that the activity in sex life was distinctly lower in a number of items.

Adult↗
PubMed1977

Adult cryptorchids: Sexual development and activity.

Plasma testosterone in 72 unilateral and 83 bilateral cryptorchids, 11-45 years of age, revealed that, from 13 years on , values of male hormone were lower than in the control group of 69 normal boys and 85 fertile and potent men. Analysis of heterosexual development by means of the HTDM questionnaire in 49 unilateral and 57 bilateral cryptorchids, aged 21-40 years, who were examined for sterility, revealed only slight social developmental retardation compared to 184 normospermic men from sterile marriages. On the other hand, examination of sexual activity by means of the SAM questionnaire in the same three groups revealed that in cryptorchids the first ejaculation is slightly later and that the frequency of nocturnal emissions in pubescence is lower. In adulthood the patients with cryptorchidism exhibit fewer signs of high sexual activity suca as repeated coitus on the same day or a high frequency of sexual intercourse. Also, there is an earlier appearance of prolonged periods of sexual abstinence.

Adolescent↗