Patenting gene sequences.
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Biomedical subjects
Publications and source records attributed to J Merz.
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270 patients who suffered from gynaecological cancer, epilepsy or diabetes mellitus were examined with a newly developed questionnaire as to their coping behaviour. In order to assess the dimensions and reliability of the instrument, the data were evaluated by different statistical methods. For the three coping patterns established by factor analysis: anxiety/withdrawal, emotional neutrality/diversion and hope/facing of illness, significant correlations resulted with the variables age and sex. The outcome of the investigation suggests that if the disease takes a favourable turn, the chronically ill patient, similarly, copes with it in a favourable manner. For the differentiation and prominence of coping patterns, the patient's subjectively experienced impairment of his physical state of health seems to play an important role.
The assessment of premorbid adjustment in schizophrenia has gained increasing interest in psychiatric research. Numerous studies have provided evidence on the predictive power of premorbid adjustment in the course and outcome of schizophrenic psychoses, but only little systematic research has been done on this topic comparing schizophrenics and healthy persons. In this study we have analyzed the premorbid life situation and social adjustment of 69 first onset schizophrenics in contrast to 60 healthy subjects. The comparisons between these samples showed significant differences for nearly all areas assessed, indicating a premorbid disablement of the schizophrenics both for quantitative and qualitative aspects of social functioning. Compared to that of healthy people, the size of the schizophrenics' social network is markedly reduced and often characterized by a strong link to their family of origin. In general, the schizophrenics fail to establish close relationships or engage in social contact. Moreover, they tend to withdraw from existing relationships, especially heterosexual ones. Even when the schizophrenics appear quite normal on formal criteria (such as partnership or employment situation), further analyses often reveal problems, e.g., conflicts at work or reticence with partners. The results of this study clearly demonstrate the necessity of assessing not only formal criteria but also behavioral patterns and emotions of the persons concerned.
This article studies the self-assessed pre/postoperative course of the psychological condition of 3 patient groups (hernia, aorto-coronary bypass and cancer patients) and healthy controls. Some consequences for clinical work are discussed.
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Brown and Birley demonstrated a triggering effect in schizophrenic disorders for life events. In our study no similar result was found. As many events were discovered in controls as in first admission schizophrenic patients for the two 3-month periods assessed: 1-3 months and 4-6 months prior to onset of an acute episode or prior to interview. But methodology used in this study differs with respect to the periods assessed: Brown and Birley used 3-week periods, we used 3-month periods. Patients as well as controls reported significantly more events for the period immediately prior to the onset or interview. We suppose that neither patients nor controls actually experienced fewer events in the second period but that they remembered more of them for the period nearer to the interview.
A new accelerated intelligence test is presented which is known as the multiple selection vocabulary test B. This is a very objective and reliable test measuring the general level of intelligence. The time of testing will be about three to five minutes in the case of persons that are free of any psychiatric disorders. Test results will be only negligibly influenced by psychic and mental disorders.
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