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Biomedical subjects

J Messer

Publications and source records attributed to J Messer.

At least 127 records · Page 7Linked to original sources
PubMed1978

[Neo-natal neutropenia induced by anti-NA 2 allo-immunization. Serological and clinical study of 2 cases in a family].

A severe neutropenia in a 2 day old newborn drew attention to anti-HLA and NA 2 antigranulocytic antibodies in the maternal serum. Close supervision from birth of a younger sibling demonstrated a neutropenia on the 5th day of life. Serological investigation showed the anti-NA 2 antibody to be responsible in both cases. A good result with total blood replacement of leucocyte-free blood in the second case would advocate this treatment in cases of severe immunological neutropenia.

Agranulocytosis↗
PubMed1977

A long term evaluation of infants who received a beta-mimetic drug while in utero.

The administration of beta-mimetic drugs to pregnant women poses the problem of possible long-term repercussions in the children born to these mothers. 42 children from women who had been treated with 60-80 mg a day of ritodrine hydrochloride (Pre-par), during a period varying from 3 to 93 days, were closely matched with infants from untreated mothers. Each child, (aged from one to 3 years), was fully investigated on the basis of: a detailed questionnaire to the mother; careful clinical examination; assessment of psychomotor development; the Denver test; electrocardiography and urine analysis. There was no statistically significant difference between the two groups for any of the variables of development that were studied. One child had left ventricular hypertrophy, which was probably incidental. It is concluded that administration of ritodrine hydrochloride to pregnant women induces no harmful long-term effects in their offspring.

Body Height↗
PubMed1976

[Severe hyperosmolarity caused by dietary error in the newborn. A disorder of particular concern in migrants].

Hyperosmolarity as a result of dietary error is a fairly common condition. It is more grave than "thirst fever", the benign reputation of which should not be taken too lightly. The consequences may be serious: death or sequelae related to vascular thrombosis or cerebral lesions. Prevention should be possible in most instances as long as obstetricians, paediatricians, midwives and nursery nurses are aware of the danger of overconcentrated milk formula. Its treatment remains fraught with hazard.

Animals↗
PubMed1975

G-6PD "ankara". a new G-6PD variant with deficiency found in a Turkish family.

A new G-6PD varient with enzyme deficiency is described in a 7-month-old Turkish boy without any hemolytic manifestation, except neonatal hyperbilirubinemia. The main characteristics of this variant were the following: Severe enzyme deficiency in erythrocytes (8% of normal), fast starch-gel-electrophoretic mobility (110% of normal), increased Ki NADPH with respect to NADP+, slightly biphasic pH curve, enzyme instability, in vivo and in vitro, decreased molecular specific activity (58% of normal).

Blood Cells↗
PubMed1975

[Hemodynamic consequences of umbilical arterial catheterization. Photoplethysmographic study].

The hemodynamic consequences of umbilical arterial infusions in newborns can be registered by photoplethysmography. Thirty-nine children were observed according to the same protocol: it was possible to recognize, on the side of the infusion, without other clinical symptoms, very early but after different times: - in 3 cases, the supression of arteriolar oscillations, back to normal after 24 hours in one case, and after several weeks in 2 cases; - in 2 cases, a transitory increase of arteriolar oscillations; - in 7 cases, an elective decrease of the arteriolar systolic pressure, with unchanged diastolic pressure. In 4/7 cases, it became normal in less than 3 days; - in 3 cases, a decrease in arteriolar systolic and diastolic pressures, during 2 days.

Catheterization↗