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Biomedical subjects

J Messer

Publications and source records attributed to J Messer.

159 records · Page 9Linked to original sources

Antenatal diagnosis of brain damage in the survivor after the second trimester death of a monochorionic monoamniotic co-twin: case report and literature review.

At 28 weeks of amenorrhea, 1 fetus of a monoamniotic twin pregnancy died. Ultrasound and Doppler investigations of the surviving twin were normal. Three weeks later, endovaginal ultrasound and magnetic resonance imaging revealed massive bilateral cerebral ischemic necrosis in the surviving twin. In utero fetal blood sampling carried out before the termination did not reveal either anemia or thrombopenia. Current data suggest that cerebral or renal ischemic complications could set in immediately after the death of the first twin as a result of a period of acute hypotension. At least 2 weeks are necessary for them to be identifiable by ultrasound. It seems that they cannot be prevented by prompt delivery of the second twin.

Abortion, Spontaneous↗

[Branhamella catarrhalis in neonatal pulmonary infectious pathology].

Bronchopulmonary infections has been described for the most part in adults. ORL and upper respiratory tract infections are encountered in children. In neonates, only conjunctivitis have been reported. In their report, the authors describes the first cases of bronchopulmonary infections due to Branhamella Catarrhalis in premature infants with respiratory distress syndrome. Three cases are described in which this bacteria has been isolated in bronchial secretions and in the culture of the nasotracheal tube. Clinical and biological features were not specific. Only orosomucoid serum level was increased. A favourable outcome was obtained by macrolides. Epidemiological survey permitted the isolation of Branhamella Catarrhalis in one of the nurse who had taken care of the neonates. Otherwise, these infections occurs in immunologically compromised hosts. Hyaline membrane disease appears most likely as an auspicious factor.

Bacterial Infections↗

[Prevention of iatrogenic effects of artificial ventilation with transcutaneous monitoring of PO2 and PCO2 in the newborn infant].

The authors have monitored Tc PCO2, Tc PO2 and mean airway pressure in 25 ventilated newborns, during 68 days. They show that the best blood gases values are not even obtained with the most aggressive artificial ventilation (A.V.). Tc PCO2 and Tc PO2 transcutaneous monitoring and mean airway pressure measurement allow an "à la carte" adaptation of the A.V. to bring in each case the most efficient and the least aggressive A.V. This method may decrease the iatrogenic complications of the A.V.

Carbon Dioxide↗

[Fetal congestive heart failure due to nodal tachycardia: in utero digoxin therapy ].

The authors report one case of fetal congestive heart failure secondary to nodal tachycardia, revealed in the 26th week of gestation. Transplacental digoxin treatment stopped the tachycardia in a few days and allowed the pregnancy to continue to term, with delivery of a normal child. This report shows the value of fetal echocardiography in cases with arrhythmias, the possibility of in utero digoxin treatment of supraventricular tachycardia and the follow-up procedures.

Adult↗

[Etiology and prevention of severe mental handicaps].

In a group of 124 children with mental retardation, a study showed 21% of chromosomal abnormalities, 26% of perinatal causes and 33% of undetermined causes. Current preventive measures are well adapted. They might be usefully completed by mandatory ultrasonographic examinations during pregnancy and promotion of birth of at-risk children in well-equipped centers for perinatal medicine. In cases when in utero transfer is not possible, transfer by specialized pediatric emergency care services should be generalized. A better supervision of families where retarded children are living would be advisable. The detection of bacterial meningitis should be improved. Finally, an active research should be undertaken in order to better dissociate and understand the as yet unknown causes of mental retardation.

Adolescent↗

[Placental anomalies and neonatal development of hypotrophic infants].

The study of 181 hypotrophic children led to the following conclusions: 1. In pregnancies preceding the birth of hypotrophic children, placenta is significantly more frequently altered than in all other cases. 2. Among all the changes observed in the structure of placenta, ischemic necrosis of placental villi seems to be the worst, in terms of immediate neonatal evolution. Hypoglycemia, especially, is most often observed in such instances. Consequently, examination of the structure of placenta allows a prognosis at the time of birth of a child with intra-uterine growth retardation; its practice should become generalized.

Adult↗

[Fetal and neonatal supraventricular paroxysmal tachycardias].

The authors report 3 cases of fetal supraventricular tachycardia which carried on into neo-natal life. In one case the tachycardia was discovered in the 35th week of amenorrhoea and was able to be followed up to term. In this respect the means of making a definite diagnosis are as follows : a cardiotocogram when one happens to be able to observe the beginning or the end of an attack (in which case a definite "plateau" shape is found) and especially a fetal electrocardiogram obtained transparietally in pregnancy or by means of an internal electrode in labour. Supraventricular tachycardia is usually of marked degree and comes in isolated episodes and is not to be confused with tachycardia that is found accompanying fetal distress, occurring in pathological pregnancies. The obstetrician can therefore delay while carrying out intensive supervision of the case, which is particularly directed to searching for signs of generalised feto-placental oedema. After birth the child should be transferred to an intensive care unit where the tachycardia, if it persists, should be reduced in order to avoid serious asystolies. The outlook for the baby if there is no congenital malformation is good, since the trouble with the cardiac rhythm is usually a reflection of lack of maturity in the cardiac conduction tissues.

Electrocardiography↗