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J Milosavljević

Publications and source records attributed to J Milosavljević.

12 recordsLinked to original sources
PubMed1989

[Familial poisoning by carbon monoxide with different ECG changes].

The paper presents the poisoning of a family of three by carbon monoxide, caused by incomplete combustion of butane gas in a central heating system, with various disturbances in conduction and ishaemic changes in the ECG. The father, mother and son were poisoned. The father had increased amylase activity in urine (507 i.u./L) and, a COHb concentration of 4.8%. An ECG registered a temporary block of the left branch of the His bundle and a negative T wave in the III lead, which continued for about two weeks. The mother had a COHb concentration of 6% and an extended PQ interval, whereas the son had 8.5% of COHb in the blood and a transient incomplete block of the right branch of the His bundle. After treatment with pressurised pure oxygen, the symptoms of poisoning disappeared, COHb concentration fell to below 1% and the ECG registered an improvement. During treatment the patients also received an infusion of piracetam.

Adult↗
PubMed1983

[Levels of serum complement and immunocomplexes in HBs antigen positive blood donors].

Blood donors who were tested twice at interval from 6 to 8 months, were HBs-Ag positive both times. The biochemical parameters for the evaluation of liver function were within normal limits. The significantly decreased values of total haemolytic activity of complement-CH50 (0,001) and Clq (0,005) and increased level of Cl Inh (0,005) point ot the activation of the complement system (Table 2, 3). The level of Cl Inh statistically significantly and positively correlates with the values of C4, C5 and with C3A, what means that it participates in the process of activation regulation (Table 5). Using the method of precipitation by means of 0,3 g/l PEG we have registered in 92% of HBs-Ag positive blood donors elevated concentrations of immune complexes and in all PEG precipitates HBs-Ag (Table 6). These findings point to the need of clinical investigation and treatment of those persons.

Adolescent↗
PubMed1981

[Complement level in serum from patients with chronic hepatitis].

In persons with chronic active hepatitis (35) and chronic persistent hepatitis (23) the CH 50 values, Clq, Cls, C4, C3, C5, and C9 as well as Cl Inh and C3A levels have been determined. The concentration changes of complement (C) were not conditioned by the existence in serum HBs. The degree of changes in values of C in all patients is in determinate relation with the levels of bilirubin, transaminases and immunoglobulins (G, M, A). The degree of determinate changes of C depends on the severity of clinical picture. The degree of Cl Inh elevation is in correlation with intensity of complement activation. The noticed dissociated values of subcomplements Clq and Cls suggest the presence of immune complexes which could influence the HBsAg detection.

Chronic Disease↗
PubMed1979

Differential diagnosis, laboratory tests and histology in 245 patients with cholestasis.

In the course of 4 years, among 11,738 admissions there were 245 (2.08%) patients with cholestasis (106 women and 139 men). Intrahepatic cholestasis (i.c.) was detected in 46.5%, and extrahepatic (e.c.) in 53.5%. The most frequent cause of i.c. were alcoholic and nonalcoholic chr. liver disease (fatty liver, chr. hepatitis, cirrhosis) (37% and 30%), acute viral hepatitis (15%) and toxic liver injury (14%) respectively. The causes of e.c. were: choledocholithiasis (44%), cancer of the pancreatic head (15%), cancer of gallbladder and extrahepatic ducts (12%) and cancer of liver (10%). The causes of c. were benigne, in 78.2%, while malignant neoplasms were present in 21.8%. Out of the multitude of laboratory tests two appeared particularly significant: glut, transpeptidase was pathologic in 81% of alcoholic liver disease, in 62% of the cases with obstructive jaundice and in 27.7% of malignant neoplasms. LX-lipoprotein examined in 52 patients was positive in 24% of i.c., and 60% of e.c. Proliferation of bile ducts was the most frequent finding in surgical liver biopsies in choledocholithiasis cases.

Adolescent↗
PubMedDate not supplied

[The yentl syndrome in women with arterial hypertension and positive findings on the echocardiography dipyridamole stress test].

UNLABELLED: The aim of this study was to assess the possible gender differences between positive (new wall motion abnormality) combined dipyridamole stress echocardiography and coronary angiography or myocardial revascularization procedures. We evaluated 127 consecutive patients (82 males, 53.5 years old and 45 females, 56.1 years old) with systemic hypertension and chest pain (angina or atypical chest pain) who underwent pharmacological stress echocardiography (dipyridamole-atropine or dipyridamole-dobutamine) for detection of myocardial ischaemia. Coronary angiography was carried out in 84 patients (58 males and 26 females). Diagnostic accuracy of the test was the same in women as in men (92.3 vs 89.1%, females vs males, respectively). Coronary angiography was done in 73.6% of male and 66.7% of female patients with positive test; the difference was not significant. Over a two-year follow-up there were 31 myocardial revascularization procedures (20 coronary surgery and 11 angioplasty), 25 in men and 6 in women (p = 0.028). There was a trend in women with positive test to have less surgery or angioplasty (28.6%) than in men (45.3%), but the difference was not significant. Cox multivariate regression analysis revealed that women were less likely to receive revascularization (relative risk for females RR = 0.1457, 95% CI 0.0416-0.5101). CONCLUSION: Although diagnostic accuracy of third generation dipyridamole stress echocardiography was not different between men and women, in patients with positive test there was a trend in women to undergo coronary angiography and coronary surgery or angioplasty in lesser degree than in men. Cox multivariate model showed low relative risk of females for revascularization procedures and possible Yentl's syndrome in studied population.

Coronary Angiography↗