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Biomedical subjects

J Modestin

Publications and source records attributed to J Modestin.

At least 73 records · Page 4Linked to original sources
PubMed1981

Patterns of overt sexual interaction among acute psychiatric inpatients.

An indepth study was carried out over 1 year on all instances of overt heterosexual interactions among acute psychiatric patients on mixed-sex intensive treatment units. Sixteen of the 1060 patients treated on the units were involved in nine instances of overt heterosexual interactions. Analysis of the interactions showed three distinct patterns, called Types 1, 2 and 3. In Type 1 interactions, overt sexual behavior approaches normality. In Type 2 interactions, overt sexual behavior is of a pronounced demonstrative quality but avoids genital involvement. In Type 3, overt sexual interaction is confined exclusively to sexual intercourse. Multiple determinants of the patients' involvements in overt heterosexual interaction are presented. The type of overt sexual interaction engaged in by inpatients depended more on each patient's history, including past sexual life, than on clinical diagnosis. As a rule, the patient's most relevant and central problems were expressed in a very distinct manner in the overt sexual interaction on the unit. Thus, a thorough investigation of every case of such interaction provides an opportunity to discern these problems rapidly and to elaborate on them therapeutically.

Acute Disease↗
PubMed1981

A fatality during haloperidol treatment: mechanism of sudden death.

The authors report a case of unexpected sudden death in a woman receiving relatively high dose of haloperidol. They postulate that drug-induced laryngeal spasm leading to cardiac arrest via vagal reflexes may represent the mechanism of neuroleptic sudden death in some cases.

Adult↗
PubMed1980

[Concerning the borderline (author's transl)].

A general survey of the borderline literature is presented. The diagnostic label "borderline" has predominantly been used in North America; nevertheless, many roots of this conception originate in the classical European psychiatry and psychoanalysis. The various diagnostic (mainly descriptive) criteria and characteristics of the borderline are discussed, as well as the most important psychoanalytic hypotheses and conceptions (such as splitting, projective identification, identity diffusion). The therapeutic principles are mentioned as well. The analysis of the surveyed literature reveals on the one hand, that a well defined borderline exists neither as a generally acknowledged clinical entity nor as a circumscribed psychopathological syndrome. On the other hand, there are three various borderline concepts clearly discernible: 1) borderline conceptualized as a form of schizophrenia, 2) borderline conceptualized as synonymous with the general category of psychopathy (personality disorder) and 3) borderline conceptualized as a special form of psychopathy.

Antisocial Personality Disorder↗
PubMed1980

Borderline: a concept analysis.

An examination of the literature concerning the borderline reveals that different authors, using different concepts of the borderline state, are describing different patient groups. Related to the background of the generally accepted psychiatric nosological classification, three borderline concepts are clearly discernible: (1) borderline equated with a forme fruste of schizoprenia, (2) borderline equated with a general category of personality disorder (psychopathy) and (3) borderline equated with a special form of personality disorder.

Antisocial Personality Disorder↗
PubMed1980

[Diagnosis of the borderline disorder].

A typical borderline case is presented, "borderline" being conceptualized as a form of personality disorder/psychopathy. The main characteristics have turned out to be 1. diversity and variability of symptoms, 2. affective disturbances and insufficient impulse control, 3. disturbed interpersonal relations, 4. pronounced suffering compelling the patient to seek treatment. The necessity of standardizing conceptions and characteristics of borderline disorders is being stressed and reporting on prototype cases considered an expedient measure to this effect.

Adult↗
PubMed1977

[Psychiatric morbidity of patients hospitalized at the internal medicine ward].

Report on two studies to investigate psychiatric morbidity in patients hospitalized in an internal medicine ward of a distric general hospital. In the first charts of 783 patients hospitalized in 1975 were evaluated retrospectively, while the second study (conducted in 1976) involved clinical assessment by the author of 244 newly admitted patients. A psychiatric diagnosis could be established in some 70% of all patients hospitalized in the internal medicine ward, and the morbidity rate in patients for whom therapy was indicated was 40%. Investigation of the medication utilized on the ward revealed that psychopharmacologic agents (chiefly given as hypnotics) were the most frequently prescribed group of drugs, whereas they were administered to 25% of patients on a regular basis (without indication as hypnotics). These high figures emphasize the need to decentralize psychiatric services and to intergrate psychiatry into internal medicine.

Adolescent↗
PubMed1977

[How blind is a double-blind trial really? Validity of controlled investigations].

During a double blind trial lasting 4 weeks (Diazepam versus Loxapin), two investigators tried to identify the given drug prematurely. Only the more experienced investigator was able to identify the two drugs (p = 0.01). His judgement was based neither on observation of side-effects nor on a clinical improvement but apparently on a summary of particular subtle effects, the cognition of which requires a specific experience. The use of an adequate comparative drug instead of a placebo in a double blind study does not completely prevent a premature decoding but should reduce this risk and therefore increase the validity of the method.

Anxiety↗
PubMed1976

[Beta receptor blocking agents in psychiatry (author's transl)].

The effects of beta receptor blocking agents in various psychiatric indications have been investigated during the last decade. The results are summarised and discussed. A final judgement of the value of beta blocking agents within the complete psychopharmacological treatment is, at present, not yet possible. They appear to have a certain therapeutic effect depending on the peripheral beta receptor blockade, at least on functional psycho- and neurovegetative cardial and circulatory disturbances as well as on anxiety states, neurotic and those caused by stress, both of these presenting primarily somatic symptoms. In other cases the results, as they now stand, present some very interesting features for further investigation.

Adrenergic beta-Antagonists↗
PubMed1976

[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].

Results of investigations concerning the correlation between plasma concentrations and clinical effect of neuroleptics and antidepressives are summarised. In the case of neuroleptics there is in general no relationship between clinical parameters of activity and plasma concentration. For antidepressives there is, in most cases, a correlation between side-effects and plasma concentrations. Whether the therapeutic effect is dependent on the plasma concentration or not, is however open to some doubt. The practical value of plasma concentration estimations during therapy with the above mentioned drugs is therefore limited. Inadequate efficacy and/or poor tolerance can occasionally be explained by estimating plasma concentrations which alone, however, scarcely allow one to make prophecies. In determination of the optimal individual dosage must continue to be an empirical process based on clinical observations and experience.

Amitriptyline↗
PubMed1975

[The problem of masked depression].

The term "masked depression" appears to be increasingly used as a diagnostic label, but underlying the label are a multitude of problems. Questions of definition, diagnosis, nosologic classification and differential diagnosis are discussed in detail.

Acting Out↗