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Biomedical subjects

J Moor

Publications and source records attributed to J Moor.

3 recordsLinked to original sources

Dentures may be radiolucent.

Diagnosing ingested dental prostheses can be difficult and delays in treatment may result in serious complications. Patients often present with a vague history and very few reliable clinical signs. In addition, the fact that dental plates are often radiolucent may lead to the diagnosis being overlooked with disastrous consequences. A case of successful diagnosis and treatment is presented, and the importance of a high index of clinical suspicion to avoid the morbidity and mortality associated with missed impacted dentures is discussed.

Deglutition↗

Preoperative chemotherapy followed by mastectomy for locally advanced breast cancer.

Six patients with advanced local-regional breast cancer were reviewed. Five out of the six patients previously had had radiation therapy as part of the initial therapy. All patients had preoperative cycles of combination chemotherapy, either CMF or CAF. The two stage III patients had greater than 75% reduction in measurable tumor mass, which allowed a conventional modified radical or radical mastectomy to be performed. Both of these patients are now disease free at 26 and 27 months. The four stage IV patients had lesser operations following the chemotherapy (two simple mastectomies, one simple mastectomy plus axillary resection, and one axillary debulking). Reconstruction utilized advancement flaps in three patients and split-thickness skin grafts in the other. None of the patients had postoperative wound problems, and none of the patients had further problems with local cancer control. All patients had combination chemotherapy starting two to six weeks following surgery. Preoperative chemotherapy followed by surgery plays an important role in management of locally advanced stage III and stage IV breast cancer.

Adenocarcinoma↗

The mass spectra of permethylated oligosaccharides.

The electron impact mass spectra of permethyl ethers of twenty-five highly purified oligosaccharides, containing first, aldohexose units only and second, at least one fructose unite, have been determined. It is concluded that spectra of these derivatives can yield considerable structural information, especially in relation to the detection of fructose units, the pyranose/furanose ratio and the position of the glycosidic linkage, and are to be preferred from this point of view to the mass spectra of trimethylsilyl ethers.

Chemical Phenomena↗