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Biomedical subjects

J Mosimann

Publications and source records attributed to J Mosimann.

11 recordsLinked to original sources

Testing the hypothesis of the multidimensional model of anorexia nervosa in adolescents.

This study statistically tested six hypothesized risk factors of the model for anorexia nervosa. Forty-three adolescents with anorexia nervosa and 85 controls were administered the EAT, EDI, and FES. In addition, 43 parents of anorexics and 85 parents of controls completed the Family History Data Sheet, the FES, and the Perfect Child Questionnaire. Three of six hypothesized risk factors were confirmed: family history of depression, feelings of ineffectiveness, and poor interceptive awareness. Log-linear analysis indicated that the hierarchical model that best fit the data had significant two-way interactions with anorexia nervosa, G2 (11, N = 128) = 65.87, p < .001. In addition, alcohol and drug abuse or dependence figured prominently in the family history of patients with anorexia nervosa. The multidimensional model for anorexia nervosa holds up as an exploratory model of this condition in the adolescent age group.

Adolescent↗

[Indications and interpretation of serologic studies in reactive arthritis].

The big number of microorganisms known to cause arthritis following infections and also her biological variety make culture methods for the etiologic diagnosis difficult if not impossible in the individual case. Diagnostic possibilities offered by serology are practically unlimited. The search for the etiology can easily be adapted to the history and the clinical picture presented by the patient. Arthritis is usually accompanied by high antibody titers, which may be explained by a strong immunological reaction of the organism and the relatively long duration of the disease. The conditions required for a satisfactory interpretation of the results are discussed. Examples of real cases will illustrate the possibilities of diagnostic serology.

Antibodies, Bacterial↗

Salmonella and Shigella infections in Switzerland, with special reference to typhoid vaccination for travellers.

This prospective study reveals that 48% of 368 salmonelloses and 81% of 43 shigelloses diagnosed within one year in the Zurich area were imported from abroad. Travellers in close contact with the local population have a higher risk of being affected by typhoid fever or shigellosis than the average tourist. The clinical course was generally mild, and there was no lethal case. As the incidence of Salmonella typhi is very low, typhoid vaccination is recommended only for high-risk travellers.

Adolescent↗

[Serodiagnosis of human Yersinia infections. Preliminary results].

Preliminary data are reported on experience with newly developed complement-fixing (CF) antigens prepared from cultures of type 3 and type 9 Yersinia enterocolitica and from Yersinia pseudotuberculosis. Antigens were immunologically potent and not anti-complementary, thus making it possible to obtain satisfactory serologic tests. The results may be summarized as follows: 1. Yersinia CF antigens do not react with sera from healthy blood donors. There was only one low titer reaction with type 9 antigen among more than 300 serum samples tested. 2. There was a high degree of correlation between results of the agglutination tests and those obtained by CF. 3. There is no cross-reactivity by CF among the three Yersinia antigens if human sera are tested. A complete crossing was, however, obtained between type 9 Yersinia and Brucella abortus. 4. Hyperimmune sera frequently showed marked cross-reactivities in both CF and agglutination tests. 5. Human sera positive for various Salmonellae do not react in the CF tests with Yersinia antigens. It is felt that the new CF antigens may become an important tool for the detection of antibodies against Yersinia enterocolitica in the diagnosis of infectious diseases.

Antibodies, Bacterial↗

[Pulmonary Actinomyces-viscosus infection].

The isolation of Actinomyces viscosus from the pleural fluid of a patient with pleuro-pneumonia and empyema is described. This is believed to be the first human Actinomyces viscosus infection in Switzerland.

Actinomyces↗

[Yersinia enterocolitica infections in the Zurich area. Bacteriologic-serological diagnosis and case reports].

It has been investigated whether in the region of Zurich there are infections caused by Yersinia enterocolitica, and, if so, whether these could readily be diagnosed by us. Both questions can be answered in the affirmative. Yersinia enterocolitica type 3 was identified in 5 of the 837 stool specimens sent to our Salmonella diagnosis unit. In 19 of the 1125 blood serum specimens the titer of agglutinin against Yersinia enterocolitica type 3 was higher than 1 : 160. Our methods of isolation and identification of Yersinia enterocolitica are described. The clinical findings were in accordance with previously published observations by different authors. In none of the cases could any other causal agent have been responsible for the symptoms.

Adolescent↗

[Study of Brazilian agricultural workers. A medico-socio-psychological study].

UNLABELLED: The general state of health of native Brazilian agricultural workers - a total of 750 people from 3 different plantations in the States of Paraná and Saso Paulo - was examined. The main interest of this study war centred on infectious and parasitic diseases, nutritional conditions as well as social, intellectual factors. OBSERVATIONS: Apart from the high number of cases of helminthiasis, amounting to 80%, the general state of health of the examined subjects was found to be good - indeed better than that of a hypothetical, comparable group of Europeans. Except for the Chagas' disease, by which 5% of the test subjects were afflicted, infectious diseases posed no serious problems. There was no case of malnutrition. The relatively lower intellectual level can not be attributed to any heriditary factor, and could definitely be improved by proper schooling. Corrective measures: Chagas: Since brick houses have replaced the wooden ones for several years, new infections are unlikely. Helminthiasis: In addition to the anthelminthic treatment, sanitary prophylactic measures should be taken. Social-intellectual factors: The following points should be emphasized: elementary schooling on the plantations; teaching at intermediary level; sewing and cooking courses; general hygience.

Adolescent↗