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Biomedical subjects

J N Bernstein

Publications and source records attributed to J N Bernstein.

3 recordsLinked to original sources

Aldicarb poisoning. A case report with prolonged cholinesterase inhibition and improvement after pralidoxime therapy.

Aldicarb is the most potent of the commercially available carbamate pesticides and is an unusual source of acute human poisonings. We present the case of a 43-year-old man exposed to aldicarb who developed severe cholinergic symptoms and progressive weakness requiring intubation for 5 days. Both his red blood cell cholinesterase and plasma pseudocholinesterase levels were depressed for a minimum of 44 hours. He demonstrated neuromuscular improvement concurrent with pralidoxime administration. The pertinent medical literature on aldicarb poisoning is reviewed.

Adult↗

Common plant ingestions.

Of the enormous number of calls regarding toxic and nontoxic plant ingestions received by the Florida Poison Information and Toxicology Resource Center each year, the majority are about accidental ingestions in the pediatric population. These tend to involve household plants ranging from nontoxic to those with life-threatening cardiotoxicity. Several recent cases of ingestions with the intent of producing hallucinogenic effects have been presented to the Poison Center. Other misadventures have resulted from the similar appearance of toxic and nontoxic plants. The three poison centers in Florida have access to toxicologic consultation to help the clinician assess the severity of a plant poisoning and to guide in treatment decisions.

Accidents↗