Biomedical subjects

J N HARRIS-JONES

Publications and source records attributed to J N HARRIS-JONES.

16 recordsLinked to original sources

PubMed1964

INTRAVASCULAR ENDOTHELIOMA (ENDOTHELIOMA IN SITU, SYSTEMIC ENDOTHELIOMATOSIS).

A woman aged 48 years was found to be suffering from intravascular endothelioma. The initial clinical presentation was the presence of red, painless swellings in the skin of the lower limbs. The other clinical features, and the histological changes in skin biopsies, are described and compared with those in the two previously reported patients. It is suggested that the condition is analogous to the pre-invasive carcinomatous states.

Female↗

PubMed1963

Insulin-binding antibodies in relation to insulin therapy.

Methods for detecting insulin binding or transporting antibodies are described, involving the use of radioactively labelled insulin (insulin (131)I). These antibodies are detected in a high proportion of patients receiving insulin, particularly those requiring large doses. The protein fractions concerned appear to be the beta and gamma globulins. The significance of the phenomenon is discussed.

Humans↗

PubMed1961

Hypercholesterolaemia and diabetes mellitus.

An association of essential hypercholesterolaemia and diabetes mellitus is postulated. Case records are included to illustrate hypercholesterolaemia secondary to acute diabetes mellitus, and essential hypercholesterolaemia, independent of, but accompanying diabetes mellitus. Whereas in the former the serum cholesterol returns to normal and its attendant clinical manifestations resolve when the diabetes is controlled, this is not so in the latter type. Evidence is presented to show that impaired carbohydrate tolerance is not a feature of essential hypercholesterolaemia.

Cholesterol↗

PubMed1958