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Biomedical subjects

J Naidu

Publications and source records attributed to J Naidu.

14 recordsLinked to original sources
PubMed1998

A case of subcutaneous infection in a patient with discoid lupus erythematosus caused by a Scytalidium synanamorph of Nattrassia mangiferae, and its treatment.

A case of subcutaneous infection caused by Scytalidium synanamorph of Nattrassia mangiferae is reported in a 24-year-old female suffering from subacute discoid lupus erythematosus. Lesions were seen on the palm of the left hand and dorsal aspect of the right hand. Histopathology of the biopsied specimen revealed light brown hyphae and single celled structures along with many inflammatory cells. The patient showed marked improvement with oral chloroquin and itraconazole orally and ketoconazole cream topically.

Adult↗
PubMed1993

Growing incidence of cutaneous and ungual infections by non-dermatophyte fungi at Jabalpur (M.P.).

A random survey of skin and nail infections was done at Jabalpur (M.P.). Out of the 80 suspected cases 60 were culture positive. Out of these 25 were of dermatophyte infection followed by 21 cases of phaeohyphomycosis, 7 of aspergillosis, 4 of hyalohyphomycosis, 2 of mixed infection in which a non-dermatophyte was associated with a dermatophyte and 1 had yeast infection. Trichophyton rubrum was the only dermatophyte isolated. Among the non-dermatophyte infections cases of Alternaria chlamydospora, Cladosporium sphaero-spermum, Curvularia senegalensis, Chaetomium globosum, Scopulariopsis brumptii, Paecilomyces variotii and Aspergillus chevalieri are for the first time documented as etiologic agent of cutaneous and ungual mycosis from India.

Adult↗
PubMed1992

Hyalohyphomycosis caused by Paecilomyces variotii: a case report, animal pathogenicity and 'in vitro' sensitivity.

A case of cutaneous infection in a 25-year-old male caused by Paecilomyces variotii is described. Animal pathogenicity studies with normal and cortisone-treated mice revealed the predeliction of P. variotii for skin and liver in both normal and cortisone-treated mice and for lungs and heart only in immunosuppressed mice. 5-fluorocytosine gave the best MIC value for P. variotii in vitro. This report documents for the first time that P. variotii causes cutaneous infection.

Adult↗
PubMed1991

Onychomycosis caused by Scopulariopsis brumptii. A case report and sensitivity studies.

Scopulariopsis brumptii was isolated from nail lesions in left hand of a 42 year-old-farmer. The direct microscopic examination of the nail samples revealed light brown, septate, branched fungal hyphae along with thick-walled spherical cells. The histopathological examination showed involvement of internal phase of the nail plate. Amongst the antimycotics tested against S. brumptii 'In vitro' oxiconazole was found to be the most active with MIC value of 10 micrograms/ml-1. This report documents the first instance of onychomycosis caused by S. brumptii.

Adult↗
PubMed1991

Onychomycosis caused by Chaetomium globosum Kunze.

In this paper we report a case of onychomycosis caused by Chaetomium globosum. The patient had lesions of the fingernails of the left hand. The direct microscopical examination of the nails showed light-brown hyphae with thick-walled cells. The histopathological examination revealed thick aggregated hyphal element in the nail plate. Amongst the antimycotics tested oxiconazole with MIC values of 0.3 microgram/ml-1 was found to be most effective in vitro against Chaetomium globosum.

Adult↗
PubMed1984

ECT, emergent dyskinesia, and depression.

Three depressed patients developed a dyskinesia directly following ECT. In each case the dyskinesia improved some time after cessation of ECT. All patients had prior treatment with an antipsychotic drug and previous diagnoses of schizophrenia or schizoaffective disorder.

Antipsychotic Agents↗
PubMed1981

Racial differences in perception of ward atmosphere.

The authors administered the Moos Ward Atmosphere Scale (WAS) to 17 black inpatients and 17 white inpatients at a VA hospital. Scores on 5 of the 10 subscales reflected significant differences on the basis of race. From these results, the authors assume that black patients and white patients perceive the same ward environment differently. They briefly discuss the treatment implications of such perceptual differences.

Adult↗
PubMed1980

The effects of geographic relocations on a general hospital's psychiatric units.

With the remodeling of general hospitals as well as the programmatic changes within hospitals, psychiatric units often have to move to a new setting. Such moves have an impact on the attitude and behavior of patients and staff. When two of three psychiatric units in a Veterans Administration hospital were forced to move to new locations within the hospital, staff tried to minimize expected negative effects of the move. The authors, using a questionnaire that assessed ward atmosphere, evaluated changes in patients and staff before and after the move. They found subjective and objective evidence that the move had the greatest negative impact on the single unit that remained in the same setting.

Adult↗
PubMedDate not supplied

Aspergillus chevalieri (Mangin) Thom and Church: a new opportunistic pathogen of human cutaneous aspergillosis.

Three cases of opportunistic cutaneous aspergillosis caused by Aspergillus chevalieri are described. The lesions were erythematous and hyperkeratotic with vesicopapular eruptions and scaling. Histopathology revealed granulomatous reaction showing polymorphonuclear leucocytes around fungal hyphae, which were broad, septate, branched and aggregated in the epidermal area. Oxiconazole and amorolfine, with a minimum inhibitory concentration of 10 micrograms ml-1, were the most active drugs against A. chevalieri 'in vitro'. A. chevalieri is, for the first time, documented as opportunistic pathogen of man.

Adult↗
PubMedDate not supplied

Chronic suppurative otitis media caused by Paecilomyces variotii.

A case of chronic suppurative otitis media is described in a patient with a chronic cold and cough. The presenting symptoms were otorrhoea, perforation of the tympanic membrane and granulation in the air cells of the left mastoid cavity. X-ray showed sclerotic mastoid and partial cellular obliteration. Histologic sections revealed aggregated fungal masses, filamentous hyphae and single-celled structures of Paecilomyces variotii. The infection responded to topical ketoconazole therapy. This is the first reported case of chronic suppurative otitis media caused by P. variotii.

Administration, Topical↗
PubMedDate not supplied

Maxillary sinusitis caused by Ascotricha chartarum Berk. (anamorph Dicyma ampullifera Boul.): a new phaeoid opportunistic human pathogen.

The first human infection caused by Ascotricha chartarum of the maxillary sinus is described. The patient, a 35-year-old woman, developed a hard bony swelling on the right cheek. Her maxillary X-ray showed complete opacity of the right maxillary antrum with a shadow of erosion. C.T. scan revealed a radio opaque mass having vacuolated appearance in the antrum. The debris removed from the antrum contained phaeoid fungal elements. At places, softening of the bone was observed. The mucoperiosteum exhibited acute inflammatory reaction and invasion by the pathogen. The pale brown to subhyaline fungal elements in biopsy tissue grew Ascotricha chartarum, a phaeoid ascomycetous fungus in culture. The patient had a smooth recovery when treated with betadine lavage and itraconazole after surgical intervention.

Adult↗