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J Neuwirth

Publications and source records attributed to J Neuwirth.

At least 19 recordsLinked to original sources

[Diagnosis of pulmonary embolism and monitoring of post-embolic changes in the vessels using pulmonary digital subtraction angiography].

The group comprises 48 patients where digital subtraction angiography revealed embolization of the lungs. Forty-four of the patients were examined on account of clinical suspicion of embolism of the lungs, in the remaining four the examination was made on account of other indications. In four instances of 48 patients where we diagnosed or suspected embolism of the lungs DSA was also used to follow up the effect of heparinization and anti-aggregation therapy in relatively extensive findings revealed during the first examination. Based on their experience, the authors summarize angiographic pictures into four morphological types: perfusion defect, localized thinning and reduction of peripheral arterioles, sudden discontinuation of lobar and segmental arteries ("cut-off") and intraluminal defects in the contrast filling of arteries. The authors evaluate objectively the advantages and disadvantages of DSA and compare in the discussion the course of the examination, as well as the results with classical angiography, with perfusion and ventilation scan and try to find the correct place in the algorithm of visualization methods when embolism of the lungs is suspected. Based on the assembled experience, DSA of the lungs can be used as the first diagnostic method or after screening perfusion scan, if the latter is available immediately after development of complaints, as the second method. The authors analyze also the reasons of the relatively less frequent and very often late indication of this examination in this country.

Adult

[The role of digital subtraction angiography in the diagnosis of pulmonary anomalies].

The authors evaluate the importance of pulmonary digital subtraction angiography (DSA) in anomalies of pulmonary tissue, the bronchial tree and vascular pulmonary malformations. In a group of eight patients, comprising unilateral pulmonary hypoplasia, pulmonary cysts, vascular malformations and pulmonary sequestrations, they analyze the asset of DSA and the place of this method in the diagnostic algorithm. Reduction of the invasive and risky character of the examination, lower costs, the possibility of immediate evaluation and subsequent processing of the picture and modification of the length of the record is one of the main advantages, as compared with classical angiography.

Adult

DSA diagnosis of pulmonary embolization from intracardial thrombus in a patient with permanent pacing catheter.

Pulmonary embolization in patients with implanted pacemakers is rare and an intracardiac thrombus attached to the distal end of a newly implanted ventricular endocardial electrode following removal of a previously implanted lead is a curiosity. We have documented such a case by digital subtraction angiography, a minimally invasive procedure that demonstrates both an intracardiac thrombus and secondary pulmonary embolization in a single procedure, which also allows simplified follow-up evaluation following therapy.

Angiography, Digital Subtraction

[Initial experience with high-resolution computer tomography in diffuse pulmonary diseases].

The authors describe their initial experience with the use of high resolution computed tomography (HRCT) in diffuse lung diseases. They analyze in detail the examination technique, different parameters of the visualization modus, aiming of the scan and the standard procedure in HRCT examinations. They demonstrate also the picture of normal anatomical structures on HRCT pictures and morphological types of changes reflecting pathological processes in the pulmonary parenchyma. In a group of 21 patients the most frequent disease was idiopathic pulmonary fibrosis or suspected fibrosis, suspected carcinomatous lymphopathy, pulmonary emphysema incl. the vanishing lung syndrome, exogenous allergic alveolitis and alveolar microlithiasis, diffuse pulmonary affections in collagenoses and Crohn's disease. When the clinical findings are considered concurrently, the HRCT picture is fairly pathognomic and contributes to the establishment of the final diagnosis. In idiopathic pulmonary fibrosis CT and HRCT give a more accurate idea of the extent, grade and frequently also stage of the disease, and as compared with a simple X-ray of the chest, it is a more accurate and more sensitive method. It may be assumed that gradually it will become a standard examination method in diffuse pulmonary diseases.

Adult

[Anomalies of the basilar and vertebral arteries that are of practical importance].

Anomalies of vertebrobasilar vessels arise as early embryonal developmental deteriorations. The majority of them concerns the position, origin and shape of the vertebral and/or basilar arteries. In three patients, reported here, the aberrations were found occasionally and contributed in no way to the clinical symptomatology. In the first patient, a fenestration of A. basilaris was found with a fork-like division on its periphery. In the second patient we noted a doubled proximal origin of the vertebral artery. One artery arose from A. subclavia sinistra, the second one from the aortic arch. Both joined thereafter the common vertebral stem at the level of C4. In the third patient, A. vertebralis originated from the aortal arch, and, at the level of the thyroid, A. thyreoidea inferior originated from it. Attention is drawn to the practical importance of such variations as a possible source of diagnostic errors during cerebral arteriography.

Adult

[Digital subtraction angiography in intracranial vascular malformations].

From a total number of 350 DSA examinations in the cervicocranial region intracranial vascular malformations were detected in 14 patients, i.e. in 4%. In six instances an aneurysm was involved, six times arteriovenous and twice a venous malformation. Using digital subtraction angiography, it is usually possible to diagnose by the intravenous or intraaortal route major findings, however, in the majority the finding serves only for orientation. For a more detailed diagnosis, in particular of small findings and findings before operation, a selective examination is more suitable.

Adult

[The significance of digital subtraction angiography in diseases of the lungs and mediastinum].

The authors present their first experience with lung DSA in a group of 75 patients. The examination was most frequently performed by instilling a contrast medium into central, less frequently into peripheral veins. The most frequent indications included tumorous lung diseases and mediastinal tumours before an operation treatment, a suspected pulmonary embolism, lung and vascular malformation. Intravenous DSA proved to be also useful in the evaluation of pathological changes of thoracic aorta.

Adolescent

[Dilatation technic in esophageal stenoses using a balloon catheter].

In dilating oesophageal stenoses by balloon catheters it becomes necessary to adapt the technique of the intervention to the type and degree of stenosis and condition of the patient. The dilatation may be successfully performed even in very narrow postinflammation, postoperation and postcorrosion stenoses. The dilatation is usually performed for the period of 30 minutes, the shortest period between interventions being twice in a week, being followed by weekly or several weeks intervals. In a careful application of the balloon catheters transnasally or transorally it becomes possible to decrease the unpleasant feelings of the patient and possible complications to a minimum.

Catheterization

Effects of total fasting in obese women. II. Acid-base balance.

Acetoacetate, beta-hydroxybutyrate, pyruvate and lactate in whole blood, the acid-base balance according to Astrup, SGOT and SGPT, and the serum and urinary sodium and potassium were estimated in 10 fasting obese women. Fasting led metabolic acidosis due to a tenfold increase of acetoacetate and beta-hydroxybutyrate, while pyruvate and lactate had a tendency to decrease. Serum and urinary sodium and potassium decreased; A tendency to increased SGOT and SGPT was observed. Sodium bicarbonate administered in general since the 8th or 9th day of fasting led in 4 to 5 days to an earlier correction of blood pH, while pCO2, actual HCO3, standard HCO3, base excess, buffer base, pO2, Hb saturation and total CO2 reached the prefasting values only several days after blood pH normalisation. The administration of NaHCO3 corrected the serum level of sodium while its excretion remained low. Bicarbonate had no influence on the decreasing trend of serum potassium, but the urinary output of potassium was stabilized. It is suggested that in fasting subjects 1. the correction of the metabolic acidosis by NaHCO3 does not reduce the rate of lipid catabolism and does not lead to fluid retention and 2. liver damage in fasting may be prevented by blood pH normalisation.

Acetoacetates

Peripheral conversion and uptake of androgens in a XXY-man with Klinefelter's syndrome.

The conversion of 3H-testosterone and the uptake of 3H-testosterone and 3H-5alpha-dihydrotestosterone were investigated in pubic skin and pubic hair follicles of a XXY-man with inadequate pubic hair. The uptake of both androgens was demonstrated in the skin as well as in the hair follicles. Similarly the activity of steroid 5alpha-reductase was present in both tissues. The total conversion of 3H-testosterone was 2-3 times higher in the patient than in control persons. In the XXY-man the major metabolites were 5alpha- and 5beta-androstanediols, whereas in the normal men 5alpha-dihydrotestosterone and 4-androstenedione were mainly formed from testosterone. An explanation of the inadequate growth of pubic hair in our patient seems to be related to a conversion of testosterone - at its low plasma level - to its relatively inactive metabolites.

Adult