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Biomedical subjects

J Nicol

Publications and source records attributed to J Nicol.

10 recordsLinked to original sources
PubMed1995

Cooperative organization of inorganic-surfactant and biomimetic assemblies.

A model that makes use of the cooperative organization of inorganic and organic molecular species into three dimensionally structured arrays is generalized for the synthesis of nanocomposite materials. In this model, the properties and structure of a system are determined by dynamic interplay among ion-pair inorganic and organic species, so that different phases can be readily obtained through small variations of controllable synthesis parameters, including mixture composition and temperature. Nucleation, growth, and phase transitions may be directed by the charge density, coordination, and steric requirements of the inorganic and organic species at the interface and not necessarily by a preformed structure. A specific example is presented in which organic molecules in the presence of multiply charged silicate oligomers self-assemble into silicatropic liquid crystals. The organization of these silicate-surfactant mesophases is investigated with and without interfacial silicate condensation to separate the effects of self-assembly from the kinetics of silicate polymerization.

Benzene Derivatives↗
PubMed1995

Prolonged parenteral nutrition for cystic fibrosis patients.

To evaluate the clinical impact of prolonged parenteral nutritional (PN) therapy on patients with advanced cystic fibrosis, we conducted a retrospective chart review of 25 cystic fibrosis patients who underwent prolonged PN (median course 295 days) at our institution between August 1988 and May 1992. The patients' survival status, change in percentage of ideal body weight, need for ongoing nutritional intervention, pulmonary function test changes, i.v. antibiotic use, and complication rates were assessed. Patients gained significant weight while receiving PN, but they lost weight when PN was discontinued. PN did not clearly improve pulmonary status. IV antibiotic therapy nearly doubled during PN. Central venous catheter sepsis rates rose from 1.29 to 3.45 per 1000 catheter days during PN therapy. In conclusion, prolonged PN promotes weight gain in cystic fibrosis patients with severe disease; however, the effect is transient and involves a significantly increased risk of sepsis.

Adolescent↗
PubMed1989

The role of structure in coreference assignment during sentence comprehension.

This paper examines the role of syntactic constraints on the reactivation and assignment of antecedents to explicit and implicit anaphoric elements during sentence comprehension. Evidence from on-line studies examining the time course of coreference processing supports the view that reactivation of potential antecedents is restricted by grammatical constraints when they are available. When structural information cannot serve to constrain antecedent selection, then pragmatic information may play a role, but only at a later point in processing.

Cognition↗
PubMed1983

[Female veterinary surgeons: a follow up study].

Questionnaires were sent out to 68 registered female veterinary surgeons in South Africa to obtain career information essential to vocational guidance. The 46 respondents represent 51,7% of the 89 female BVSc graduates up to 1981; their average age was 33,3 years, 63% were married, 30,4% were from the Pretoria area, 60,9% were living in the Transvaal, 52,2% had had 6 and more years of veterinary experience. All the comparisons done indicated that the response group was representative of the women who had obtained the BVSc degree from the University of Pretoria. Some of the more important findings were the following: No less than 97,8% of the response group are at present actively engaged in veterinary work--73,9% on a full-time basis. Asked what they would choose now, 84,8% of the respondents declared that they would choose veterinary science once again; 67,4% would like to see their daughters enter the profession. The most important reason for this positive attraction towards veterinary practice was given as "job satisfaction experienced". Respondents indicated the things that they liked about veterinary practice: factors intrinsic to the job like surgery, pathology and research topped the list followed by the opportunity to work with and help animals and also the variety experienced in their work. The most important grievances were firstly the general attitude and actions of the public--callousness of animal-owners and inconsiderate behaviour towards practitioners. Long and irregular hours, administrative red tape and insufficient technical help were also complaints.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1968

Evaluation of discordant laboratory data in patients with thyroid disorders.

The usefulness of the various tests of thyroid function has been evaluated over a three-year period. It is concluded that an uptake test and estimation of the serum protein-bound radioactive iodine (PB (131)I), supplemented as required by the protein-bound iodine (PBI), remain the best routine tests of thyroid function. Forty-five patients who gave discordant results on these tests over this period have been studied in detail and the value of other tests of thyroid function has been explored.

Adolescent↗