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J Niland-Weiss

Publications and source records attributed to J Niland-Weiss.

3 recordsLinked to original sources

A microcomputer-based distributed data management system for a large cooperative study of transfusion associated acquired immunodeficiency syndrome.

This paper describes the details of a microcomputer-based, distributed data management system in the acquisition of data collected in a large multicentered cooperative investigation of transfusion-transmitted acquired immunodeficiency syndrome (AIDS). Clinical, virological, and immunological data are obtained from six clinical centers and six central laboratories using a variety of hardware components and software packages. Data are merged and processed on a mainframe computer at the Biostatistics Office at the University of Southern California. The advantages and disadvantages of this system are discussed relative to the dynamics of the study, the magnitude and nature of the database, and the organization of the distributed centers involved.

Acquired Immunodeficiency Syndrome↗

Pregnancy in sickle cell disease.

Risks associated with pregnancy for mothers with sickle cell disease and their infants have decreased markedly during the last decade. Among 79 women with sickle cell anemia (156 pregnancies), maternal death decreased from 4.1% before 1972 to 1.7% after 1972; their infants' fetal and perinatal death rates decreased from 52.7 to 22.7% (P less than .05), and from 33.3 to 27.3% among infants of women with sickle hemoglobin C disease. There has been a significant improvement in birth weight specific mortality and an increase in number of weeks' gestation from 34.7 to 37.4 (P less than .05). A higher percentage of sickle hemoglobin C disease mothers completed their pregnancies with no complications (43%) when compared with sickle cell anemia mothers (21%), thus identifying a subset of women for whom pregnancy does not represent an increased risk. These results are attributed to improvements in state-of-the-art medical, obstetric, and perinatal care.

Adult↗

Computerized evaluation of clinical experiences in the training of health professionals.

The Physician Assistant Program at the University of Southern California School of Medicine in Los Angeles established a computerized data base in 1980 to evaluate the clinical experiences of its students. Data on patient encounters are collected by means of "patient contact cards." The data focus on three main areas: patient demographics, diagnoses/therapeutics, and student responsibility levels. A FORTRAN computer program was written to produce summary reports for individual students as well as for the entire class. The information generated can be used to ensure adequate experience in each clinical area, document the student's background for employers, serve as a basis for curriculum revision, and allow evaluation of the adequacy of clinical services in the community. The computer program is transferable to other institutional locations as well as to other types of health care provider training programs. The design of the patient data system, the computerization process, the implementation of the program, and its applications are discussed.

California↗