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Biomedical subjects

J Norum

Publications and source records attributed to J Norum.

9 recordsLinked to original sources
PubMed1992

[Intestinal lymphoma presented as multiple intestinal polyposis].

Primary gastrointestinal lymphoma is a rare condition. It constitutes approximately 5% of all lymphoid malignancies. Primary lymphomas of the intestinal tract rarely present as multiple polyposis. We describe such a patient who was treated with chemotherapy. The treatment of choice is surgery when possible. Chemotherapy is used in addition when high grade non-Hodgkin lymphoma is revealed. Chemotherapy should be used for patients who are unable to undergo curative resections. Prognosis is poor for patients with a non-resectable disease.

Aged↗
PubMed1992

[Accidents with radioactive pollution. Can we do something?].

Nuclear accidents are a cause of widespread fear. Treatment of patients exposed to high doses of total body irradiation has very often been ineffective. The use of hematopoietic growth factors may be a new way of treating these patients. This article describes results from studies of total body irradiated animals and clinical experience from treating humans who have been involved in nuclear accidents. G-CSF or GM-CSF administered within three hours after a nuclear accident seems to be of value. Surprisingly, so far bone marrow transplantation seems to be of limited value. Intravenous transfusions of thrombocytes and red blood cells, and the treatment of burns and gastrointestinal symptoms, are important parts of the medical therapy.

Accidents↗
PubMed1992

[Treatment of advanced anal cancer].

Anal carcinoma affects between 30 and 40 Norwegians every year. The disease is twice as frequent in women as in men. It is usually located in the anal canal only, and is cured by a combination treatment with chemotherapy and radiotherapy. Metastatic anal carcinoma has a poor prognosis. We present two such cases. 5-fluorouracil in combination with cisplatin or mitomycin C can give responses even in advanced cases. Radiotherapy may also be of value. In view of the difference between norwegian clinics in the treatment of anal carcinoma, there would appear to be a need of a Scandinavian or international study based on standardized treatment.

Aged↗
PubMed1991

[Infusor--an aid in cytostatic therapy].

Infusor is a pump controlled by an elastomeric balloon. It has been used for continuous infusion of morphine, heparin, antiemetics and different kinds of cytostatics. The article presents our experience of Infusor when used for intravenous infusion of fluorouracil to patients with head and neck cancer. Infusor had many practical advantages. It provides a new possibility for continuous administration of cytostatics at home. A disadvantage was a slightly unstable infusion velocity.

Antineoplastic Agents↗
PubMed1991

[Merkel cell carcinoma].

Merkel cell carcinoma is a rare disease. During the last five years we have treated two patients at the Cancer Department, University Hospital Tromsø. These two cases are reported. Immunohistochemical analysis and electron microscopy are important for a precise diagnosis. The primary treatment is surgery. There is usually a need for supportive radiotherapy. The disease is also sensitive to chemotherapy.

Aged↗
PubMed1990

[Cerebral metastasis in Hodgkin's disease].

The article describes the case history of a 31 year old woman with a solitary intracranial metastasis from Hodgkin's lymphoma, and reviews the relevant literature. Metastasis to the central nervous system from Hodgkin's disease is uncommon. This affection is usually a result of metastasis to the meninges or bone, or of direct extension from paracranial or paraspinal lymph node involvement. Hematogenous metastasis of Hodgkin's disease confined to the brain is rare. Affection of the central nervous system is most common in lymphocyte depletion Hodgkin's disease. A higher frequency is seen in advanced clinical stages. The prognosis is poor.

Adult↗
PubMed1990

[Chylothorax].

A 51 year old man developed chylothorax from a non-Hodgkin lymphoma located in the abdomen. The main causes of chylothorax are trauma and malignant disease. The condition is quite often idiopathic. The treatment is usually a combination of surgical treatment, conservative treatment, high voltage radiation and/or pleurodesis with a sclerosing agent.

Chylothorax↗