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Biomedical subjects

J O Bond

Publications and source records attributed to J O Bond.

At least 19 recordsLinked to original sources
PubMed1987

Antibody response after a two-year intradermal booster of rabies human diploid cell vaccine.

A study was undertaken to evaluate the effectiveness of a low dose of rabies human diploid cell vaccine administered intradermally for preexposure booster inoculation. Seventy-six volunteers received a 0.1-ml dose of rabies human diploid cell vaccine intradermally, approximately 2 years after their primary series. Though only 25 (32.9%) had a titer less than 0.5 IU/ml before the booster, all had a postbooster titer of greater than or equal to 4.0 IU/ml 3 weeks later. Five of 73 (6.8%) reported an allergic reaction after the booster.

Adolescent↗
PubMed1970

Winter vomiting disease in Florida students.

On 14 November 1967 an investigation was begun at the University of South Florida to determine the cause of an increased number of gastrointestinal illnesses on campus. An estimated 300 students suddenly became ill with nausea, vomiting, abdominal pain, and diarrhoea. While at first food poisoning was suspected, no common food, water, or toxic exposure could be found. The data collected were most consistent with Winter Vomiting Disease. This entity is characterized by acute gastrointestinal illnesses which may occur in epidemic form in residential schools between September and March. Most investigators suspect that a viral agent is responsible for the illnesses, though attempts to isolate a virus have been unsuccessful. The incubation period in the University outbreak was estimated at 28 hr., and contact was the most likely mode of transmission. The outbreak illustrated that Winter Vomiting Disease in residential institutions may be an accentuation of the gastrointestinal illnesses occurring simultaneously in the community at large.

Communicable Diseases↗
PubMed1969

An evaluation of influenza immunization: influence of route of administration and vaccine strain.

A field study was undertaken in Tampa, Fla., to assess the efficacy of subcutaneous and aerosol methods of administering vaccine, and to compare the protection afforded by bivalent (A2 and B) influenza virus vaccine and by A2/Hong Kong/68 virus vaccine. Further objectives of the study included a comparison of the effectiveness of single-dose and 2-dose immunization. Approximately 2100 volunteers received, in a double-blind manner, both an injection and an aerosol administration on 2 occasions 3 weeks apart. The results showed that aerosol administration gave a lower over-all protection rate, although the booster dose seemed to have a marked effect. The protection afforded by A2/Hong Kong/68 virus vaccine was considerably greater than that afforded by the bivalent vaccine, particularly when administration was subcutaneous. Results are also given on the occurrence of side-effects and on the correlation between cigarette smoking and the occurrence of influenza-like illness.

Aerosols↗