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Biomedical subjects

J O Ojukwu

Publications and source records attributed to J O Ojukwu.

15 recordsLinked to original sources

Asymptomatic rotavirus infection within Benin City urban community, Nigeria.

This study was carried out in Benin City urban community, Nigeria as a follow-up of an earlier study carried out on patients admitted to the University of Benin Teaching Hospital. The aim of the present study was to determine the prevalence of asymptomatic rotavirus infection amongst urban children and adults. Eight hundred and twenty one subjects from 200 homes were screened for rotavirus infection between August and December 1990. The 821 stool samples collected from the subjects (541 children and 280 adults) were subjected to studies at the University of Benin Teaching Hospital. Detection of rotavirus antigen was done by the ELISA method. The overall prevalence of asymptomatic rotavirus infection in this study was 30.8%. The results reflect a high source of reservoir for spread of rotavirus infection within the community.

Adolescent↗

Incidence and parametric determinants of post-operative wound infections in a university teaching hospital.

The incidence and determinants of post-operative wound infections in the University of Nigeria Teaching Hospital, Enugu was studied. During the period of study (July 1983-June 1984) 218 surgical operations from adult males and females were investigated. The overall infection rate was found to be 27.98 percent. The incidence rate in clean wounds was 14 percent; in clean-contaminated 50 percent; in contaminated 66.66 percent and in dirty wounds 80 percent. Factors such as age, sex, nature of surgery, and antibiotic prophylactic cover which were found to have influenced the infection are discussed. The study underlines the need for a policy that will promote a more rational use of antibiotics, strict observance of ward aseptic routines and the establishment of effective Infection Control Programme where non exists.

Adolescent↗

Complete rectal prolapse in Enugu, Nigeria.

The case records of thirty patients (21 male and 9 female) aged 8 to 62 years treated for complete rectal prolapse by operation over 5 years were studied. The results of treatment were compared with those in seven consecutive patients treated more recently by posterior rectopexy. Thiersch operation has been attended by an unacceptable high rate of reoccurrence, recurrent sepsis and faecal impaction. We recommend that is use should be abandoned. Anterior resection, usually more successful, is also associated with significant morbidity. We consider it too formidable an operation for a benign condition. We have found posterior rectopexy to be simple, safe and effective and we recommend it for the surgical treatment of complete rectal prolapse.

Adult↗

Malignant disease of the colon, rectum, and anus in Nigerian Igbos.

An account is given of 5 anal and 36 colorectal cancers occurring in Nigerians of the Igbo ethnic group. The rectum was the site of predilection for colorectal growths, and most rectal growths occurred in males. In contrast to the situation in the Western world the disease is rare, affects relatively younger patients, and is often advanced at presentation. Dietary factors probably play no significant role in the aetiology of the disease.

Adult↗

Unusual craniocerebral injuries from nailing.

Three cases of unusual craniocerebral injuries caused by deliberate driving of nails into the head are reported. All injuries were on or near the midline in the parietal area and the nails measured about 10 cm. Two of the patients experienced little pain during the procedure and did not lose consciousness. The extraction of each nail was extremely easy. The only patient who died was admitted in a coma and had meningitis.

Adult↗

Invasive thymoma (a case report).

A 10-year old Nigerian boy was admitted to hospital with a history of swelling in the neck, change of voice, dysphagia and dyspnoea of 2 weeks duration. He died on the 2nd day of admission. Autopsy revealed a thymoma infiltrating the thyroid, trachea and neck muscles and transforming the tracheal lumen into a slit like space. The condition is considered worthy of record on account of its rarity and of the short clinical course terminating in death. The authors feel that the most important factor in determining the prognosis of thymoma is the presence or absence of gross invasion.

Airway Obstruction↗

Infarction of accessory spleen.

A rare disease that can mimic acute appendicitis is infarction of accessory spleen. It may occur in children and is difficult to diagnose preoperatively. Greater awareness of this entity may show not only that it is associated with other intraabdominal anomalies but also that it is more common in the tropics than elsewhere. Two cases are reported.

Acute Disease↗

Male breast carcinoma in eastern Nigeria--a 13 year study.

A 13 year review of carcinoma of the male breast in an African Population is presented. Its incidence, Clinical presentation, diagnosis and modalities of treatment are critically analysed. The literature is reviewed and such topical issues as risk factors, prognostic indices and modern concepts on the possible aetiological mechanisms of development of human breast cancer are discussed. Finally suggestions are offered on possible strategies to improve the bleak survival rate.

Adult↗