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Biomedical subjects

J O Sipperley

Publications and source records attributed to J O Sipperley.

16 recordsLinked to original sources
PubMed1991

Vitreous surgery for retinal detachment associated with choroidal coloboma.

We report the results of vitreous surgery in seven eyes with retinal detachments caused by retinal breaks at the margin of, or within, a choroidal coloboma. All seven eyes (100%) were reattached; visual acuities in five (71%) of the seven eyes improved from preoperative levels. Vitrectomy was combined with air-fluid exchange and endodrainage through preexisting retinal breaks or planned retinotomies in all but one of the cases. Part or all of the rim of the choroidal coloboma in six eyes underwent endophotocoagulation. The two eyes that did not experience postoperative visual improvement underwent intraoperative endolaser treatment 360 degrees around the optic nerve. If peripapillary endophotocoagulation is performed, especially through the papillomacular bundle, nerve fiber damage may occur and prevent visual recovery, despite retinal reattachment. For eyes with retinal detachment associated with choroidal colobomas involving the optic nerve, postoperative laser treatment through the papillomacular bundle may be preferable.

Adolescent↗
PubMed1990

Vitrectomy for epiretinal membrane with Candida chorioretinitis.

Four eyes underwent vitrectomy and epiretinal membrane dissection for tractional retinal detachment (RD) or macular pucker associated with Candida chorioretinitis. The epiretinal membranes were vascularized and, in three of four eyes, were associated with full-thickness retinal scars, presumably at the site of previous active Candida chorioretinitis. The epiretinal membranes were successfully removed in all four cases. Visual results depended on the degree of macular pathology and the presence and location of a full-thickness retinal scar.

Adult↗
PubMed1987

The management of subretinal gas following attempted pneumatic retinal reattachment.

Pneumatic retinopexy is a recently described procedure for treating retinal detachments with cryotherapy and intraocular gas injection, rather than scleral buckling. Prospective studies are underway to assess its safety and efficacy. One potential complication of this technique is persistent detachment due to subretinal gas. We report seven cases of subretinal gas following attempted pneumatic retinal reattachment. In all cases, multiple fish-egg gas bubbles were present following injection; some of these bubbles gained access to the subretinal space during the early postoperative period. The subretinal gas gave the detached retina a pearly, dome-shaped, refractive sheen. Three cases were managed by positioning the patients' heads to allow the subretinal gas to pass through the retinal break back into the vitreous cavity. One case underwent successful scleral buckling that closed the retinal break despite the presence of a small subretinal gas bubble. Three cases required vitrectomy, air-fluid exchange, and cryotherapy or endolaser treatment. In five of the seven eyes the retina was eventually reattached successfully.

Adult↗
PubMed1987

Linear nevus sebaceous syndrome.

The linear nevus sebaceous syndrome is a rare disorder first described in 1962 in two cases by Feuerstein and Mims. As originally described, it consisted of the triad of the characteristic midline facial linear nevus sebaceous of Jadassohn, seizures, and mental retardation. The authors have followed a patient with this syndrome from birth to age 8 and although he does demonstrate several neurologic and ocular abnormalities, he enjoys normal intelligence and has never suffered seizures. The features of this syndrome and several new ocular findings demonstrated in this case are described. Based on our long-term follow-up of this patient and our review of the reported cases to date, the authors suggest that the triad for this disorder should be changed to include the midline facial linear nevus sebaceous of Jadassohn, neurologic abnormalities which may, but not necessarily, include seizures and mental retardation, and ophthalmologic abnormalities.

Arachnoid↗
PubMed1986

Air travel and intraocular gas.

The safety of air travel for persons with intraocular gas after ocular surgery has been in question since the mid 1970s, when the use of intraocular gases after vitrectomy became widespread. After vitrectomy, air-fluid exchange was performed on six Rhesus monkeys. During simulated air travel in an altitude chamber, intraocular pressure rose an average of 42 mmHg with intraocular air volumes as small as 0.25 cc. Hypotony was observed after return to ground level in all cases. Transient central retinal artery occlusion and pupillary block was observed. Patient safety and comfort is endangered during air travel with very small volumes of intraocular gas.

Aircraft↗
PubMed1984

A prone bed.

Explore the source record for details and available documents.

Beds↗
PubMed1983

Intraocular foreign body from a nylon line grass trimmer.

Nylon line grass trimmers are commonplace in America's lawn armamentarium. As their number has increased, so has the potential for ocular injury from objects thrown from these tools. A patient of ours was injured by an intraocular piece of nylon line thrown from one of these tools. The patient required removal of the foreign body, lensectomy, and anterior vitrectomy to rehabilitate her eye. This report again demonstrates the need for eye protection when using any type of lawn equipment. We think manufacturers of these products should label them to show that eye protection is necessary for the safe use of these tools.

Accidents, Home↗
PubMed1981

Histopathologic evaluation of adhesive properties of early lesions in diathermy and cryopexy.

We examined the histopathologic appearance of both cryopexy and diathermy lesions, ten to 60 minutes after application in the rabbit retina. Both lesions showed immediate subretinal fluid accumulation. Thus we would not substantiate the speculation that a diathermy lesion might have greater immediate adhesive strength than a cryotherapy lesion. This explains the clinical experience that retina tends to slip with either modality when trying to treat giant retinal tears.

Animals↗
PubMed1981

Histopathologic evaluation of adhesive properties of early lesions in diathermy and cryopexy.

We examined the histopathologic appearance of both cryopexy and diathermy lesions, 10-60 min after application in the rabbit retina. Both lesions showed immediate subretinal exudation. Thus, we could not substantiate the speculation that a diathermy lesion might have greater immediate adhesive strength than a cryotherapy lesion. This explains the clinical experience that retina tends to slip with either modality when trying to treat giant retinal tears.

Adhesiveness↗
PubMed1978

Small melanomas of the choroid.

We reviewed 38 cases of small choroidal melanomas on file in the Eye Pathology Laboratory of Bascom Palmer Eye Institute, Miami. Clinical and histopathological features of these cases were noted, and clinical follow-up information was obtained for 36 (95%) of the patients. Two tumor deaths occurred among the 18 patients that had a possible follow-up period of six years of more, yielding a tumor death rate of 11%. Retrospective analysis of clinical records and photographs permitted us to correlate the presence or absence of documented tumor growth with the degree of mitotic activity.

Adolescent↗
PubMed1978

Traumatic retinopathy in primates. The explanation of commotio retinae.

We have produced experimental commotio retinae in 12 owl monkeys by blunt trauma. The ophthalmoscopic and fluorescein angiographic appearance of this contrecoup lesion is identical to the acute traumatic retinal opacity in humans. We examined these eyes by light and electron microscopy from 4 hours to 12 weeks after injury. Immediately after injury, the only abnormality is disruption of the receptor outer segments. From one to six days after trauma, many receptor cells undergo degeneration. The retinal pigment epithelium phagocytoses the degenerating outer segments, occasionally migrating into the retina. There is no extracellular retinal edema. The opacity of commotio retinae seems to represent disrupted receptor cells. Visual loss may result from permanent loss of receptors. The pigment epithelial response to traumatic receptor damage is similar to that observed in experimental retinal detachment and light-induced retinal damage.

Animals↗
PubMedDate not supplied

Autosomal dominant preretinal vascular loops.

Preretinal vascular loops are a congenital malformation usually occurring in otherwise normal fundi. These anomalies consist of vessels, most commonly arteries, that spiral into the vitreous and return to the otherwise normal retinal vascular system. The authors present two members of a family with preretinal vascular loops and two members with other vascular anomalies. The inheritance pattern in this group is autosomal dominant.

Adult↗