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Biomedical subjects

J O Stadaas

Publications and source records attributed to J O Stadaas.

At least 73 records · Page 4Linked to original sources
PubMed1978

Somatostatin inhibits gastric motility in response to distention.

Gastric motility and plasma gastrin concentration have been measured in 6 healthy volunteers before and after stepwise gastric distention. Distention was performed by filling a flaccid thin-walled bag, which was connected with a low pressure transducer for measuring intragastric pressure variations. Stepwise increase in gastric volume from 0-600 ml caused graded increases in gastric motility. No significant change was seen in the plasma gastrin level. When gastric distention was performed concomitantly with constant infusion of somatostatin (0.05 mg/h and 0.50 mg/h) in the same individuals on different days, motility was significantly reduced, without any changes in the plasma gastrin concentration. It is concluded that somatostatin, which probably plays a role in the gastro-intestinal tract, may have a physiological effect in the regulation of gastric motility too. This motility effect of somatostatin seems to be independent of any effect on the gastrin concentration.

Gastrins↗
PubMed1978

Total body suspension in the treatment of burns. Report of two cases.

Total body suspension by skeletal traction was used in the treatment of two children with severe circular truncal burns. The authors do not know of any previous reports on complete body suspension, and the demonstration of the possible treatment of burn injuries in this way is considered important. The favourable aspects of the treatment, i.e. prevention of infection and pressure sores, easier nursing, physiotherapy and handling during operations, are emphasized.

Baths↗
PubMed1975

Intragastric pressure/volume relationship in the normal human stomach.

Intragastric pressure/volume relationship was studied twice in 8 healthy volunteers. Basal pressure and rhythmic contractile activity in response to defined volume loads were recorded. Reproducibility and precision of the parameters were evaluated. It is concluded that recording of the intragastric pressure/volume relationship is a valuable method for the evaluation of gastric motility, and it is well suited for clinical application. It is harmless and easy to perfrom. The reproducibility of the method and the precision of the parameters used are satisfactory.

Adult↗
PubMed1975

Intragastric pressure/volume relationship before and after proximal gastric vagotomy.

The examinations were performed before and after proximal gastric vagotomy (PGV) in 10 patients with duodenal ulcer. A flaccid plastic balloon located in the corpus-fundus region was stepwise filled with known volumes of water. Post-operative insulin tests were negative in 8 patients and late positive in two. Basal and pentagastrin-stimulated acid output were reduced by a mean of 88 and 62 percent, respectively. Intragastric pressure was significantly increased after PGV, whereas rhythmic contractions were reduced in all cases. It is concluded that PGV interferes with gastric motility and adaptation to volume variations.

Adult↗