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Biomedical subjects

J Ochsner

Publications and source records attributed to J Ochsner.

11 recordsLinked to original sources
PubMed1999

The surgical knife.

Explore the source record for details and available documents.

Equipment Design↗
PubMed1992

Experience with a new woven prosthesis.

The search for the ideal vascular graft is a dream that has eluded surgeons for centuries. Since the introduction of the fabric vascular prosthesis in 1952 by Voorhees, Jaretzki, and Blakemore, a wide variety of materials and designs have been tested. Dacron has withstood the test of time in both the knitted and woven types. Each of these graft designs has its own advantages and disadvantages, but we believe that the interlock construction of the Ochsner series grafts provides a solution to the problems associated with the earlier woven grafts while maintaining the advantages of the woven construction: (1) unraveling has been eliminated, and fraying has been reduced by the use of the interlock stitch; (2) the graft has been made soft and pliable by using three low-twist yarns, avoiding chemical impaction of the yarns, and utilizing a loose crimp; and (3) nonfixation of the pseudo-intima has been corrected by using low-twist, highly filamentous yarns which allow ingrowth of tissue for good fixation.

Blood Vessel Prosthesis↗
PubMed1991

"Shaggy" aorta syndrome with atheromatous embolization to visceral vessels.

Spontaneous atheromatous visceral embolization from diffuse aortic atherosclerotic disease is an unusual and poorly understood entity. We have reviewed our experience with 88 patients who suffered atheromatous embolization from a "shaggy" aorta. Visceral embolization was evident in 36 patients (40.9%). Nine were treated nonoperatively with three patients dying within a week of presentation and an additional five patients dying within five years due to continuing renal and intestinal embolization. Surgical correction was undertaken 28 times in 27 patients. Endarterectomy or graft replacement of the aorta did not necessarily prevent visceral infarction or renal failure. Extra-anatomic bypass with ligation of the distal external iliac arteries appears to be associated with the lowest morbidity and mortality. Anticoagulation of these patients does not prevent embolization and may be contraindicated for long-term management.

Aged↗
PubMed1990

Heparin, the miracle drug: a brief history of its discovery.

Heparin is a drug used widely in almost every field of medicine; nevertheless, very little is known about its discovery. Jay McLean, a second year medical student at Johns Hopkins University, discovered this wonderful drug in 1916 while performing research in the laboratory of W.H. Howell, MD. This is a brief account of the story told by Dr McLean before his death.

Heparin↗