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J Olaison

Publications and source records attributed to J Olaison.

4 recordsLinked to original sources

Tonsillotomy in children with tonsillar hypertrophy.

Tonsillectomy is one of the most frequent surgical procedures carried out on children. Obstructive sleep apnea syndrome, caused by tonsillar hypertrophy, has been attracting increasing interest and tonsillectomy is often performed as a result of this indication. Regardless of the indication, the main aim of tonsillectomy has always been to remove the tonsils completely. The present study was undertaken in order to investigate the effect of two different surgical techniques, tonsillectomy and tonsillotomy, on clinical symptoms in children with symptoms of obstructive sleep apnea syndrome due to tonsillar hypertophy. The study was conducted as a prospective, randomized trial comparing the clinical effects of standard tonsillectomy and tonsillotomy using a CO2 laser. Forty-three children aged 2-9 years were included. Both groups of patients experienced comparable relief from symptoms of snoring and apneas at follow-up after 3 months and 2 years. There was no significant statistical difference between the two groups of patients in terms of both short- and long-term effects on clinical symptoms. Tonsillotomy caused no measurable bleeding during surgery. Postoperative pain and distress were less pronounced in the tonsillotomy group according to visual analog scale evaluations made by patients, parents and nursing staff. In conclusion tonsillotomy appears to be the less traumatic surgical method in cases of upper airway obstruction in children caused by tonsillar hypertrophy.

Child↗

Spectral analysis of heart rate variability during desflurane and isoflurane anaesthesia in patients undergoing arthroscopy.

BACKGROUND: We studied the effect of desflurane (DES) and isoflurane (ISO) on heart rate variability (HRV) using power spectral analysis (PSA) of RR-interval in 30 patients undergoing arthroscopy, prior to induction, during anaesthesia and up to 3 h of recovery. PSA can distinguish low-frequency (LF) component and respiratory sinus arrhythmia (RSA) that are known to reflect predominantly sympathetic and parasympathetic activity, respectively. METHODS: After premedication with diclofenac and midazolam the anaesthesia was induced with propofol and maintained during spontaneous ventilation with either DES or ISO added to a mixture of nitrous oxide and oxygen. ECG and transthoracic impedance respirometer data were recorded. Power spectra were calculated with an autoregressive modelling method. RESULTS; Total power (PTOT) and individual power in two frequency bands of the HRV spectrum (PLF, 0.05-0.15 Hz and PRSA) decreased after induction of anaesthesia in both groups. At 60, 120 and 180 min of recovery the PTOT was back to control-value in the DES group but remained reduced in the ISO group. Calculated as normalised units, the PLF (nPLF) predominated over the PRSA (nPRSA) during control situations and during recovery. The reverse was the case during maintenance of anaesthesia. Thirty minutes after induction and during surgical stress the ISO group showed higher heart rate compared to the DES group as well as compared to control. CONCLUSION: DES and ISO produced similar alterations in studied parameters during the maintenance of anaesthesia. The differences observed between the groups during recovery may indicate an early intact neural reflex control system among the subjects exposed to DES. These results suggest that DES and ISO reduce the total autonomic neural system activity and alter the balance between sympathetic and parasympathetic activities in a comparable way during maintenance of anaesthesia. A more rapid recovery phase among the subjects exposed to DES is linked to differences in pharmacokinetic properties of the inhalation agents.

Adult↗