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Biomedical subjects

J Orłowska

Publications and source records attributed to J Orłowska.

At least 19 recordsLinked to original sources

[Chronic gastritis in children: evaluation after eleven years].

UNLABELLED: Chronic gastritis (CG) was diagnosed in 38 of 130 children with abdominal pain treated between 1980-1982. After eleven years, 20 of the 38 patients with CG were re-examined clinically and gastroscopically. Six gastric biopsies for hitopathological examination and two for CLO tests in each patient were taken. In 13 of 20 additional staining for H. pylori was done in the biopsy specimens take 11 years ago. In 95% (19 of 20) patients, CG and H. pylori infection were found. Thirteen of them (all examined) had already been infected with HP in childhood. Gastritis had progressed or remained unchanged in 90% (17 of 19) patients in the corpus and in 75% (15 of 20) in the antrum. All 6 patients who had duodenal ulcers (DU) in childhood had recurrences of DU. Thirty-one percent (4/13) of patients with persisting CG that had no ulcers previously, now had DU or erosions. All 19 patients with CG and HP infection received triple therapy. In 6 of 7 those regression or disappearance of CG and HP eradication were seen re-examined. CONCLUSIONS: CG which began in childhood progresses or persists until adulthood in all H. pylori - positive patients. We suggest that children with H. pylori-positive CG should receive anti-H. pylori treatment.

Abdominal Pain↗

[Behcet's syndrome with esophageal and intestinal involvement].

A case of 22-years old man with Behçet's syndrome is presented. Apart from typical aphtous ulcers in the mouth and on the scrotum the patient had oesophageal ulcerations and inflammatory changes in the ileum. During 8 years follow up the patient had several bleeding episodes from the gastrointestinal tract that required blood transfusions.

Adult↗

Short- and long-term results of colonoscopic polypectomy in children.

Eighty-four colorectal polyps of up to 3.3 cm in diameter were removed with the diathermy snare during 48 colonoscopies on 42 children, aged 2 to 18 years (mean, 7.4 years). Most polyps were juvenile and the majority were located in the sigmoid colon (55%) or rectum (37%). No complications related to medication, colonoscopy, or snare polypectomy were observed. The two presenting symptoms, rectal bleeding and anemia, disappeared soon after polypectomy in all but one patient with adenomatous polyposis coli, subsequently operated upon. Follow-up examinations, including total colonoscopy, performed 4 months to 7 years (mean, 25 months) later did not reveal abnormalities in any of the 37 children whose previously removed polyps were juvenile. The authors conclude that endoscopic snare polypectomy is an effective and safe treatment for colorectal polyps in the pediatric age group.

Adolescent↗

[Correctness of diagnosis of celiac disease based on personal data].

A way of coeliac disease diagnosis was assessed in 348 children, Only 14% of patients has been examined according to ESPGAN recommendations and in the proper time. Diagnosis has been completed in 123 patients, and coeliac disease has been diagnosed only in 38 of them. The I biopsy has not been performed in 96 children, the II biopsy--in 136 children, gluten-free diet has not been observed in 105 children after the I biopsy. Other causes of diagnostic failures included: prolongation of the consecutive stages and improper histological evaluation, change of biopsies order, erroneous clinical evaluation. Diagnosis according to ESPGAN recommendations is practically very difficult and time consuming. Immunological markers of coeliac disease (IgA EmA, ARA) should lead to simplification and adjustment of those recommendations in Poland.

Adolescent↗

[Role of coloscopy in diagnosis and treatment of large bowel diseases].

Coloscopy is the most accurate method of evaluation of the whole large bowel. The main indications for this examination are doubtful radiological changes in the colon and unexplained intestinal symptoms, bleeding in the first place. Coloscopy plays also an important role in the differential diagnosis of colitis and in the oncological follow-up of patients after polypectomy or with long-standing ulcerative colitis. The therapeutic use of coloscopy includes removal of polyps and foreign bodies, control of bleeding, and laser photocoagulation of neoplasmatic lesions. Since 1973 in the Department of Gastroenterology of the Postgraduate Medical Center 2360 diagnostic coloscopies were carried out in 1838 patients. The most frequent diagnoses were polyps (34%) and large bowel cancer (12%). Various forms of colitis were diagnosed in 7% of patients, and all other diseases jointly in 11% of cases. In 36% of patients the large bowel showed no changes, in spite of undoubtful indications for coloscopy. Many of these patients were spared explorative laparotomy. By means of diathermic loop 808 colorectal polyps were removed in 421 patients. Rare complications of this procedure were bleedings (1.5%) and peritoneal irritation symptoms without perforation (0.25%). Adeneomas prevailed among polyps. Seventeen patients with invasive cancer in adenoma were treated successfully only endoscopically.

Colonic Diseases↗