PubMed HealthSearch

Biomedical subjects

J Ordás

Publications and source records attributed to J Ordás.

11 recordsLinked to original sources

[Changes in serum and urinary levels of phosphorus in pregnant women, induced by effect of milk supplementation].

It was studied the levels of phosphorus in serum and urine in two groups of pregnant women. One group was advised to follow their usual intake and the other to supplement the diet with 750 ml of milk. A control group of healthy non pregnant women were conformed to the same protocol. Pregnant women that followed their usual intake had the same levels of serum phosphorus and maximum phosphate transport as controls. Pregnant women who had taken milk supplement showed in the second and third trimester of pregnancy significantly lower serum phosphorus and maximum phosphate transport levels than controls and also with respect to pregnant women in the first trimester. It suggests a possible influence of diet on these parameters. Both groups of pregnant women showed hyperphosphaturia through the three trimesters.

Adult

Sex differences in uric acid metabolism in adults: evidence for a lack of influence of estradiol-17 beta (E2) on the renal handling of urate.

The serum urate concentration of adult women, which is lower than in men of a similar age, is thought to be related to a higher renal clearance of urate in women, possibly due to their higher plasma estrogen levels. Intersexual differences in the renal handling of uric acid was assessed in 9 normal adult women and 9 normal age-matched men. Women showed a significantly lower serum urate concentration as compared to men (3.5 +/- 0.3 v 4.9 +/- 0.7 mg/dL, P less than 0.001), higher fractional excretion of urate (9.8 +/- 1.0 v 7.3 +/- 0.8%, P less than 0.001), and significantly lower tubular urate postsecretory reabsorption (67.2 +/- 1.6 v 76.6 +/- 1.4% of secreted urate, P less than 0.01). To test whether plasma E2 has a uricosuric effect we administered estradiol valerate and estradiol benzoate to either oophorectomized or adult women. Plasma E2 levels and urinary total estrogen excretion increased significantly in both groups but the treatment failed to significantly modify serum urate or the fractional excretion of uric acid. Furthermore, in 4 normal adult women, the tubular phases that modulate the renal excretion of urate were not significantly influenced by increased plasma E2 levels. We conclude that in comparison to men of a similar age, the lower tubular urate postsecretory reabsorption of adult women is in accordance with the intersexual differences in uric acid metabolism. Plasma E2 does not influence renal handling of uric acid or serum urate levels.

Absorption

Continuous recording of fetal pH during labor.

58 fetuses were monitored during labor, recording simultaneously F.H.R. U.P. and subcutaneous pH using an electrode by Stamm. The values of subcutaneous pH were correlated with 98 samples of capillary blood and 46 of umbilical vein blood. The correlation indices were 0.649 and 0.39, respectively. A selection of the 44 good quality records correlated with the corresponding 68 samples of capillary blood, gave an correlation coefficient of 0.95. The possible clinical use of this technique to monitor the fetus during labor is presently under discussion.

Arteries