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Biomedical subjects

J P Bossé

Publications and source records attributed to J P Bossé.

9 recordsLinked to original sources
PubMed1983

Pedicle graft epiphysis transplantation.

Transfer of a graft taken from the iliac crest apophysis of 48 immature dogs was studied as a means of repairing an epiphysiodesis constituting more than 50% of the growth plate area. Four groups of dogs were studied. In Group I the graft was pedicled on the superficial circumflex iliac vessels and reimplanted in situ. In Group II the pedicled graft was transferred to the groin area as an island graft. These two control groups demonstrate the conservation of growth activity when the graft is pedicled on its epiphyseal vessels. In Group III the graft was transferred to the distal epiphyseal area of the femur after resection of the portion of the growth plate (approximately 2/3) located inside the perichondrial ring, with conservation of 80% of the outer portion of the cylinder. Microsurgical revascularization was achieved by using the saphenous vessels. In Group IV (the control group for Group III) the latter technique was used without revascularization. Roentgenography was performed for nine months after operation. The specimens were studied by tetracycline labeling and histologic and histochemical examinations. Results indicate that a well vascularized graft functions as a dynamic catalyst for regeneration of the resected portion of the growth plate and prevents the formation of bony bridges between the epiphysis and metaphysis by possible activation of the peripheral groove of Ranvier.

Animals↗
PubMed1982

Pseudoaneurysms of the radial artery. Importance of microsurgery. Apropos of a case.

Following a case of pseudoaneurysm of the radial artery, curiously a rare pathological entity, the authors reviewed the literature, which consists of a maximum of 50 publicized cases. The arteriographic, plethysmographic and clinical studies as well as the anatomic and physiologic findings, all seem in favor of a treatment consisting of restoration of the vascular permeability of the principal arterial axes of the forearm (radial and ulnar arterial axes). Conservative treatment may expose the affected limb to a latent or immediate functional impotency, which may be more or less serious. The authors propose a microsurgical technique, with venous interposition grafting, for a better short or long term result, and also to replace the loss of substance secondary to the resected pseudoaneurysm.

Adult↗
PubMed1979

Clinical study of a new antikeloid agent.

An old healing drug has been assessed and found to be of clinical value in stopping the inflammatory phase of hypertrophic scars and keloids. So far, this drug has no known side effects other than occasional mild gastric intolerance and allergic reaction. Our findings are well supported in the literature. The effect of the drug on other forms of connective tissue anomalies that present an inflammatory phase is similar to that on keloids, gradually brining scars to the maturation phase. Our results on this will be published later. Madecassol has also been shown to have a preventive effect on burn and postoperative hypertrophic scars. It compares favorably in effectiveness with compression bandaging, and gives more lasting results than intralesional cortisone or radiation therapy. Finally, Madecassol has a placebo effect of 29%-well within acceptable limits.

Adult↗
PubMed1979

Immediate flap reconstruction after excision of basal cell carcinoma of the face.

The authors review 175 basal cell carcinomas of the face, treated primarily by surgery. The overall cure rate was 97%. Among these cases, 53 were treated by excision and immediate local flap reconstruction. Analysis of results in the latter group encourages the use of this method for virgin, untreated tumors provided basic rules of surgical oncology are followed. Furthermore, it has a definite advantage cosmetically over more conservative methods. If radiotherapy has been the initial treatment, however, immediate reconstruction after excision of a recurrent tumor should be contemplated reluctance.

Adult↗