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J P Calderone

Publications and source records attributed to J P Calderone.

4 recordsLinked to original sources

Intraocular pathology of trisomy 18 (Edwards's syndrome): report of a case and review of the literature.

The ophthalmic histopathology is detailed in a case of trisomy 18 (Edwards's syndrome). In addition to the ocular pathology already reported, previously unreported findings of iris stromal hypoplasia, abnormal lens shape, and decreased ganglion cells in the retina are noted. The ophthalmic histopathology associated with this syndrome and the relationship of several genetic disorders to their ocular manifestations are discussed.

Anterior Chamber↗

Pathologic processing of vitrectomy specimens. A comparison of pathologic findings with celloidin bag and cytocentrifugation preparation of 102 vitrectomy specimens.

Specimens obtained from 102 vitrectomies were processed by cytocentrifugation and celloidin bag techniques. The histopathology obtained with each procedure was compared with respect to cellular and tissue findings. Forty-five percent of cases had identical findings by the two techniques. Quantitative analysis of the discrepancies revealed better cellular recovery and identification by cytocentrifugation, and similar rates for the recovery and identification of tissue elements. Qualitative analysis showed better demonstration of tissue histopathology using celloidin bag thin sections. Thus, pathologic analysis was more complete when the two techniques were used together than when either was used alone.

Centrifugation↗