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Biomedical subjects

J P Dubecq

Publications and source records attributed to J P Dubecq.

At least 19 recordsLinked to original sources
PubMed1992

[Placenta praevia percreta with bladder invasion: a case report].

The authors report a rare case of placenta praevia percreta with bladder invasion giving rise to the need to carry out an emergency hysterectomy in order to stop the bleeding. The literature when analysed showed the possible outcome of this complication in a woman who had already had a caesarean section and who had placenta praevia that required a second caesarean. In this situation it is almost inevitable that a hysterectomy has to be carried out to stop the bleeding. The hysterectomy should be a total hysterectomy but this can be difficult because of the invariable "fusion" that takes place between the uterus and the posterior wall of the bladder. What has to the done bladder can range from simple closure of a hole in the bladder to ureteric diversion with reimplantation of the ureter depending on how badly the bladder has been invaded. In our case after a sub-total hysterectomy had been carried out with simple closure of the bladder, it was necessary to re-operate to treat a fistula between the bladder and the cervix.

Adult↗
PubMed1992

Idiopathic arterial calcification in a stillborn complicated by pleural hemorrhage and hydrops fetalis.

We report a case of idiopathic arterial calcification in a stillborn. As usually noted in this rare entity, the pregnancy was complicated by a polyhydramnios. The postmortem examination showed generalized arterial calcification, periarticular calcific deposits, and a large pleural hemorrhage. The causes of fetal hydrops in idiopathic infantile calcification are discussed, and, in the present case, the absence of myocardial ischemic lesion suggests that the fetal hydrops and the fetal death could have been caused by the bulky blood clot that was present in the right pleural cavity. The pathogenesis remains undetermined, but a primitive inherent defect of the elastic elements seems to initiate this disorder.

Aorta↗
PubMed1988

Renal, pancreatic and hepatic dysplasia sequence.

A renal, pancreatic and hepatic dysplasia sequence (RPHD sequence) was found in a male premature baby who died a few minutes after birth. Autopsy documented multicystic dysplastic kidneys, a dysplastic pancreas with dilated ducts, cysts, fibrosis and inflammatory infiltrates, prominent portal tracts containing dilated bile ducts and hypoplastic lungs. Other organs were normal. This triad constitutes a "dysplastic sequence" and was first reported by Ivemark et al. as "familial dysplasia of kidneys, liver and pancreas". Since then, this combination of abnormalities has been named "polycystic dysplasia" and "renal-hepatic-pancreatic dysplasia", but mostly "Ivemark syndrome", at the risk of being confused with asplenia-cardiac anomaly syndrome, which was reviewed by Ivemark et al. and also bears Ivemark's name.

Humans↗
PubMed1988

[Uterine rupture after tubal reimplantation].

The authors report a case of rupture of the right cornu of the uterus in the ninth month of pregnancy in a woman who had had her right tube implanted into her uterus. This complication is considered, in the discussion, to be rare. It is very difficult to prevent it happening during pregnancy. It would seem that a prophylactic caesarean operation should be carried out if the insertion of the placenta is in the area of the implantation.

Adult↗
PubMed1988

[Anorexia nervosa and pregnancy].

We report the case of a pregnancy associated with severe anorexia nervosa. The patient weighed 33 kg for 1 m 51 at conception. The pregnancy was obtained during a spontaneous cycle. Despite nutritional and psychological case, the patient continued to lose weight and weighed only 28 kgs at 33 weeks of amenorrhea, when she gave birth to a hypotrophic child of 1130 gr after artificial starting. The case provides discussion of the relation ship between anorexia nervosa and pregnancy.

Adult↗
PubMed1987

Cyclopia-otocephaly association: a new case of the most severe variant of agnathia-holoprosencephaly complex.

This report describes a new case of true cyclopia with otocephaly and additional brain malformations (alobar holoprosencephaly). This is a very rare occurrence involving lack of cleavage of the prosencephalon and disturbed development of the first branchial arch. An inductive defect of the prechordal mesoderm is considered as the cause for this malformation, which is a part of agnathia-holoprosencephaly complex.

Abnormalities, Multiple↗
PubMed1985

[Anterior sacculation of the pregnant uterus persisting until the 34th week].

The authors report a case of retroversion of the uterus with anterior sacculation that carried on to the 34th week of pregnancy without any functional troubles. Caesarean section made it possible to deliver a child weighing 1910 g. There were no adhesions found behind the uterus to fix it in retroversion. This clinical case has given the authors a chance to go through the principal elements in this case that evolved in such an unusual manner.

Adult↗
PubMed1983

[Isolation from a pregnant woman of a serum protein responsible for inhibiting an in vitro cytotoxicity reaction].

A non specific immunosupressive factor able to block an in vitro cytotoxicity reaction is demonstrated in the serum of pregnant women. A solution containing this blocking factor is obtained by gel filtration and precipitation of plasma by polyethylene glycol 4 000. Then after immunisation of rabbits the immune serum can be used for affinity chromatography. An alpha 2 glycoprotein has been separated which inhibits the in vitro cytotoxicity reaction and whose molecular weight determined by gel filtration and polyacrylamide gel is about 200 000 daltons.

Blood Proteins↗
PubMed1982

[Immunologic phenomena in habitual abortion].

12 women with recurrent abortions are investigated for various immunological parameters. Couples studied shared several HLA antigens, those women do not develop HLA' antibodies and cellular cytotoxicity against their husband. Their serum has an abnormal glycoprotein, migrating in the alpha globulin zone, precipitating with anti beta globulin serum. The women studied with recurrent abortions never possessed the Blocking Factor present in the serum of pregnant women, able to inhibit a cellular cytotoxicity reaction in vitro. It is proposed a reliable and simple test which could inform on the outcome of abortions.

Abortion, Habitual↗
PubMed1982

[Pregnancy in the diabetic woman].

The authors review ten years of caring for pregnant diabetic women. They adhered rigidly in these ten years to two fundamental principles, which were the need to ensure rigorous control of blood sugar levels, and the value of waiting to the 37th or 38th week before starting labour whenever the fetus did not seem to be particularly at risk. Their attitude, which has stayed remarkably constant, is different from that of many other authors who during this same period started by stopping the pregnancy prophylactically between the 34th and 36th week but later allowed labour to start sometimes spontaneously at a later stage as knowledge of feto-maternal mechanisms increased and methods of supervising these patients improved.

Birth Weight↗