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Biomedical subjects

J P Fournet

Publications and source records attributed to J P Fournet.

At least 19 recordsLinked to original sources

[Volvulus of the small intestine in a 10-year-old child with malrotation].

We report a case of complete volvulus of the small bowel in a ten-year-old child. This major complication of incomplete malrotation of the primary digestive loop usually occurs within the first few months of life. Our unusual clinical observation is the opportunity to point out that vomiting and abdominal pain may be overlooked, with the volvulus then appearing to be the first manifestation. Two other points are discussed: limitation of the length of bowel removed by performing two procedures 24 hours apart, and use of continuous reinstillation of the digestive chyme during postoperative nutritional management.

Child

[Neonatal cardiac rhabdomyoma and phakomatosis].

A large cardiac rhabdomyoma was discovered before delivery in a neonate, whose outcome was fatal. The baby and her mother had both cutaneous lesions suggestive of tuberous sclerosis, and the mother's sister had died from Von Hippel Lindau disease. The association of a cardiac rhabdomyoma and a tuberous sclerosis in the same patient is not uncommon, but the existence of Von Hippel Lindau disease in a member of the same family seems to be exceptional.

Angiomatosis

[Meconium aspiration syndrome. Determination of a prognostic index].

A study was undertaken on 54 cases of meconial aspiration in order to establish a prognostic index allowing the early estimation of the risk of occurrence of refractory hypoxia. In order to do so, the factors statistically related to the occurrence of refractory hypoxia were taken into account. These factors consisted of the first arterial blood gas determination, first chest x-ray film and the initial Silverman index. A value was assigned to each parameter, with respect to the corresponding percentage of observed refractory hypoxias. The sum of the values determined the prognostic index, which varied from 6 to 25. For a high-risk threshold fixed at 15, sensibility was 78%, specificity 90% and the predictive value 84%. For an index between 16 and 20, 70% of patients developed refractory hypoxia. Occurrence was 100% for an index above 20 and refractory hypoxia occurred early. On the contrary with indexes between 6 and 14, occurrence was 15%. The calculation of this index might help clinicians in their therapeutic decisions.

Apgar Score

[The thyroid gland of the newborn infant and postnatal iodine overload].

Severe iodine-induced hypothyroidism was recently diagnosed in several neonates raising the responsibility of the iodine antiseptic agents routinely used in these patients. Postnatal iodine overload due to cutaneous application of these agents (povidone iodine and fluorescinated alcoholic-iodine solution) was studied in 5 patients. Thyroid function studies were performed in iodine-overload neonates and in control neonates with comparable gestional age. Results indicated strong evidence of cutaneous absorption of iodine from the antiseptic agents used, leading to hypothyroidism in 12 of them. The frequency and the severity of thyroid dysfunction was closely related to the degree of prematurity. Full recovery was observed in all cases after withdrawal of the iodine-containing agents. It is therefore recommended to avoid any postnatal use of iodine preparations in neonates, mainly in preterm infants, and to use iodine antiseptic agents with great caution, when necessary during the neonatal period.

Anti-Infective Agents, Local

[Severe bronchiolitis in the newborn (apropos of 13 cases)].

Bronchiolitis in newborns is a frequent infection, usually with a good prognosis. But there are also more severe forms, better known now, endangering the vital prognosis. The authors report the experience of an infant intensive care unit, where 13 cases of severe bronchiolitis were treated. After considering the etiological circumstances, they envisage the physio-pathological problems. Clinical and paraclinical signs are described. The authors particularly insist on the treatment of severe bronchiolitis using respiratory reanimation. In many cases, assisted ventilation with tracheal intubation helps to get over the worst part. Treatment of severe bronchiolitis remains today essentially symptomatic, but the practice of the appropriate treatment enables in most cases to cure the disease.

Age Factors

Collodion baby.

The study of 198 collodion babies, 29 personal cases and 169 from the literature was undertaken. The collodion membrane with spontaneously desquamate between the 15th day and 3rd month of life. During the neonatal period one third of the infants die due to pulmonary complications or infection. The collodion membrane seems to have an increased permeability. The desquamation is followed by a relapse which leads to different keratinization disorders, most frequently nonbullous congenital ichthyosiform erythroderma.

Humans

[Enteric cyst and pulmonary sequestration. A non-fortuitous association. Apropos of a case].

The authors report a case of associated malformation of the posterior mediastinum consisting of enteric cyst and bronchopulmonary sequestration. The interesting aspect of this case is that these 2 malformations were not simply juxtaposed but connected by an individual bronchus, thus reinforcing the hypothesis that bronchopulmonary sequestration can be consequence of an abnormal bud born of the primitive anterior digestive tract.

Bronchopulmonary Sequestration