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Biomedical subjects

J P Lazareth

Publications and source records attributed to J P Lazareth.

7 recordsLinked to original sources
PubMed1997

Dorsal mesencephalic lipoma with inferior collicular hypoplasia: a case report and review of literature.

Intracranial lipomas are rare lesions the pathogenesis of which is still a matter of debate. We report the case of a patient presenting an asymptomatic lipoma located in the quadrigeminal and supra-cerebellar cisterns. The lipoma was associated with hypoplasia of the right inferior colliculus and of the rostral part of the vermis. Analysis of the relationships between neural tube and meninges prompts us to propose that the primary event of this malformation is a defect of the neural anlage which gives rise to both nervous dysplasia and lack of meningeal induction responsible for lipoma development.

Adult↗
PubMed1993

Diffuse primary leptomeningeal gliomatosis.

A 38 year old patient developed multiple cranial nerve palsy, seizures and progressive alteration in consciousness. CSF examination revealed tumor cells and a tentative diagnosis of leptomeningeal carcinomatosis from an unknown primary tumor was made. Treatment with intrathecal methotrexate and cranial radiation therapy was started without effect. At autopsy widespread leptomeningeal gliomatosis originating from a previously unknown astrocytoma of the hippocampus was found.

Adult↗
PubMed1989

The lateral cutaneous branches of the dorsal rami of the thoraco-lumbar junction. An anatomical study on 37 dissections.

Thirty-seven dissections have shown that the skin of the low back is innervated by the lateral branches of the dorsal rami of T12 and LI in 22 cases (60%) or T12 L1 and L2, in 10 cases (27%) or T12 L1 and L2 receiving an anastomosis from L3 in 5 cases (13%). The most medial nerve crossed the iliac crest through a rigid osseo-aponeurotic orifice located 7-8 cm from the midline which was seen compressing the nerve in 2 instances. This pattern of distribution may sometimes explain unilateral low back pain.

Adult↗
PubMed1988

[Anatomical study of the cutaneous innervation of the lumbosacral region. Application to the physiopathology of certain lumbalgias].

30 dissections have confirmed that the skin of the gluteal area is innervated by the posterior branches of T12 and L1, 19 times out of 30 (64 p. cent) or T12, L1 and L2, in 8 instances (26 p. cent) or T12, L1 and L2 receiving an anastomosis from L3, in 3 instances. This explains certain lumbo-gluteal pain coming from the dorso-lumbar area ("low lumbalgias of high origin"). In addition, the posterior branch, the most medial (most of the time L1, sometimes L2) goes through an osteo-aponeurotic channel formed by the iliac crest below and the dorso-lumbar fascia above. This channel, located at 7 or 8 cm of the spinal process, may be at the origin of a neuropathy. It projects at the same level in relation to the mid-line as the iliac insertion of the ilio-lumbar ligament. The latter seems impossible to feel as it is too deep and hidden by the superficial aspect of the iliac crest. Lumbalgias, sometimes related to a strain of this ligament, seem to be, most of the time, the result of an irritation of the posterior branch of L1 or L2.

Back Pain↗