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Biomedical subjects

J P Monneau

Publications and source records attributed to J P Monneau.

At least 19 recordsLinked to original sources
PubMed1991

[The early diagnosis of cancer of the breast remains insufficient. A study of breast monitoring in women over 50 years of age in Lorraine-Champagne].

Although breast cancer in women over 50 years of age can be detected by physical examination and mammography, in our region many women of that age do not benefit from a satisfactory breast surveillance: 52.4% of women who had a general check-up between February and May 1989 have their breast examined by a physician once a year or more often; only 30% had a mammography less than three years ago; 34.2% examine themselves at least once a month. Overall, only one out of four women aged over 50 is under satisfactory breast surveillance; this small group of women is characterized by a personal history of breast disease or a family history of breast cancer. Women aged between 50 and 59 years tend to have more regular breast examination than older women. Social or geographical particularities do not seem to provide a significant explanation.

Age Factors↗
PubMed1990

[Thoracic radiography in detecting heart diseases].

Within the scope of a physical examination, more than 147,000 patients from the Eastern part of France, were examined and had a chest X-ray, between 1982 and 1987. Seven physicians read those radiographs and reported their findings. After discussion of an interindividual variation noted between the seven physicians, the authors present the major findings of this study: relation between a cardiovascular anomaly discovered on the radiographs and a high blood pressure; relation between a cardiovascular anomaly discovered on the radiographs and one or several electrocardiographic anomalies; relation between anomaly of the cardiovascular silhouette as seen on the radiographs and increased levels of triglycerides and cholesterol in young adults.

Adult↗
PubMed1988

[Biological constants in migrants].

Until now, clinical chemists, clinicians, physicians dealing with the problem of migrant biology dispose only reference limits established for an autochtone population. But can these really be applied? We compared 28 blood constituents of a migrant population with those of the french population. We defined five geographic areas: Italy, the Iberian Peninsula, Northern Africa, Northern and Central Europe and the Near and Middle East.

Adult↗
PubMed1987

[Knowledge, behavior and attitude with respect to cardio-vascular diseases].

972 males and females more than 25 years old were asked by a self-questionnaire about cardiovascular disease (CVD): what do they know and how? What do they think they should do to prevent it? What do they personally do? What do they expect from physicians, society, people themselves? Findings indicate that CVD is regarded as an important problem by most of people. One in two subjects worries about heart disease. 70 p. 100 know at least one cardiovascular disease (infarct more often). 40 p. 100 can quote causes of CVD, emphasizing eating-habits, smoking and drinking, way of life. A correspondences analysis allows to establish a typology of responses: it makes appear clear differences in information according to social class, differences in concern about CVD linked namely with personal disease's experience, differences in psychological attitudes towards CVD's risk. Findings lead to set the problem of turning preventive knowledge into effective changes in health behaviour.

Adult↗
PubMed1987

[Cardiological and morphometric profile of migrants in northeastern France].

Currently, practitioners are confronted with the biological problems of migrants and have at their disposal for comparison only reference values established on autochtonal populations. Can these figures be used? From the population living in North-East France, we have established five groups of individuals originating from definite geographical areas: Italy, Iberian peninsula, Northern Europe and Central Europe, North Africa, Near and Middle East, in addition to the French. By means of a multiple regression analysis, we looked for and effect due to the geographical origin of the patients in order to describe specific characteristics of cardiovascular and morphometric examinations and read them accordingly. This study demonstrates the existence of several population groups: patients from the Near and Middle East and North Africa; immigrants from Southern Europe and Northern and Central Europe natives.

Adult↗
PubMed1986

[Epidemiology of minor electrocardiographic anomalies predictive of the occurrence of ischemic cardiopathy].

Common electrocardiographic manifestations (CEM) are predictors of ischemic heart disease (IHD). If precursors of the disease, their risk factors should be similar to those of IHD. This hypothesis has been assessed on results of multiphasic screening recorded in 1976 and 1981, in 1,347 45-65 year old men. Risk factors are social class (blue collar relative risk rr = 2.3), physical activity at work (sedentariness rr = 2.4), systolic blood pressure, no beer consumption and blood urea nitrogen with an exponential risk curve. Cholesterolemia, smoking, diabetes mellitus, overweight and uricemia are not predictors of CEM incidence within 5 years. These results support the idea that CEM are partially asymptomatic expression of IHD; they also have another significance. Subgroups should be individualized and analysis yielded on larger samples. Correlation analysis has been performed between IHD mortality and beer consumption on basis of French counties. A positive correlation (r = 62, p less than 0.01) is opposed to individual results.

Coronary Disease↗
PubMed1982

[Changes in blood pressure figures after a 5-year interval. Analysis of factors for predicting future hypertensives].

11 351 adults were observed five years after a first multiphasic screening at the centre de médecine préventive in Nancy (France). 1 424 became hypertensive. A discriminant analysis was performed on the predictive value within five years of systolic and diastolic blood pressure, body mass index, serum cholesterol, and uric acid, and heart rate. A discriminant variable was calculated by combination of all these parameters. Blood pressure seemed to have by far a stronger discriminative power than all the other variables though they were already disturbed at first screening. Discriminant variable is more predictive than each variable separately. However, further studies should be needed on the predictive value of pathophysiologic factors of hypertension before warranting preventive use of antihypertensive drugs.

Adult↗
PubMed1981

[The epidemiology of asthma in Lorraine. A method of Study (author's transl)].

The authors undertook an epidemiological study to held useful criteria to identify asthma sufferers. A simple questionnaire was used asking three questions: - Do you wheeze on breathing? - Do you have attacks of breathlessness during the night? - Do you have asthma? 7,904 people were questioned at the Centre for Preventive Medicine at Vandoeuvre-les-Nancy over a year and 1,062 gave a positive response to at least one question. The replies were sub-divided into 5 groups according to the pattern of response and were then given a further clinical assessment as follows: - A sensitivity test for house dust allergy; - A bronchial sensitivity test to Acetylcholine; - The level of blood eosinophilia; - Presence or absence of a family history of asthma. The results were then compared to a matched group of controls who gave a negative reply to all three questions. The authors concluded that the term asthma should only be used by people who recognize themselves as asthmatics and can identify at least one trigger factor in their symptoms. One frequently finds in such people : a family history of asthma, a positive allergy test to the house dust mite, and eosinophilia. On the other hand those with only one or two symptoms (dyspnoea or wheezing) without recognizing themselves as asthmatics had little evidence of a family history of asthma, a sensitivity to the house dust mite comparable to controls and no eosinophilia; in these people there was a striking relationship to tobacco consumption. The Acetylcholine test shows little discriminative value in an epidemiological study of this nature; asthmatics could not be separated from patients with chronic air-flow obstruction, particularly when due to tobacco. It would be helpful to find a test of bronchial hyperactivity which could be used epidemiology. As a result of this study it is possibly to place the prevalence of asthma in the South of Lorraine in the range of 1.7 to 3.6% of the population.

Acetylcholine↗
PubMedDate not supplied

Biochemical values of immigrant groups in north-east France.

Laboratory-test results for a population of immigrants living in north-east France revealed differences between the concentration of the blood constituents of immigrants and native French people. By immigrants we mean persons now living in France but coming from other geographical locations such as Italy, the Iberian Peninsula, northern or central Europe, northern Africa, or the Near or Middle East. Multiple regression analysis confirmed the need to establish reference limits in immigrants for many blood constituents because of a significant shift of the curve relative to that for the French population. We have determined appropriate reference limits, for some ten blood constituents in each group of immigrants.

Adolescent↗