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Biomedical subjects

J P Papp

Publications and source records attributed to J P Papp.

At least 19 recordsLinked to original sources
PubMed1996

Endoscopic appearance of cryptosporidial duodenitis.

Cryptosporidial oocyst infection is a common cause of diarrhea in patients with AIDS. Concomitant symptoms can include crampy abdominal pain, nausea, vomiting, and anorexia. Esophagogastroduodenoscopy is then useful for delineating potentially treatable pathogens. We report a case of cryptosporidial duodenitis with characteristic endoscopic findings, biopsy correlate, and a review of the current literature. The endoscopic appearance illustrated strongly suggests proximal small bowel mucosal involvement with cryptosporidial oocysts.

AIDS-Related Opportunistic Infections↗
PubMed1995

Primary linitis plastica carcinoma of the colon and rectum.

Primary linitis plastica of the colon or rectum is a rare entity. Only 85 cases of this type cancer have been reported in the English medical literature. We report two cases, including the oldest known patient presenting uniquely with a sigmoid volvulus and another patient presenting with fecal incontinence and perianal pain. Linitis plastica of the colon or rectum is characterized by presentation in younger patients and is associated with metastatic disease, a high mortality, and insidious growth, often making detection difficult. A high degree of suspicion must therefore be held; a low threshold for endoscopic and echoendoscopic diagnostic intervention also should be maintained. Endoscopic ultrasound provides a unique view of its circumferential infiltrating pattern for diagnosis and staging, but further experience is necessary to establish whether the early use of endoscopic ultrasound favorably impacts mortality.

Aged↗
PubMed1991

Management of upper gastrointestinal bleeding.

As the number of elderly Americans dramatically increases over the next three decades, as the amount of NSAID usage in the elderly continues to increase, and as the incidence of ulcer disease continues to increase in the elderly, upper gastrointestinal endoscopy will play an increasingly important role in the management of gastrointestinal hemorrhage. Initial efforts should be directed toward stabilizing the patient and obtaining a history and physical examination. As the number of associated diseases increases in a patient with gastrointestinal hemorrhage, so does risk of mortality. Therefore, it is important to promptly identify the site of bleeding and to stop active or recurrent bleeding by the application of endoscopic therapy. Intravenous sedation should be given cautiously to achieve conscious sedation in a monitored patient. A skilled endoscopist should be available to perform endoscopy and apply the therapeutic modalities of electrocoagulation, photocoagulation, or injection therapy for bleeding or nonbleeding vessels or sclero-therapy for esophageal varices. The key to success is to identify the site of bleeding and then act on the finding as clinically indicated. By doing so, it appears that the cost of hospitalization and the mortality in the elderly patient are reduced.

Aged↗
PubMed1991

The visible vessel.

Explore the source record for details and available documents.

Gastrointestinal Hemorrhage↗
PubMed1983

[Bipolar electrocoagulation in active upper gastrointestinal hemorrhage. Results of a prospective, non-controlled, multicenter study].

This is a report on a prospective, non-controlled, and multicenter trial using a new bipolar electrocoagulation unit (BICAP system) in patients with active upper gastrointestinal haemorrhage. From November 1980 to June 1982 55 patients have been treated. In 87% the bleeding could be stopped by electrocoagulation. In 27% rebleeding occurred. The mortality of upper GI bleeding in this series was 10.9%.

Acute Disease↗
PubMed1980

Electrocoagulation of actively bleeding Mallory-Weiss tears.

Thirty patients with upper gastrointestinal bleeding due to a Mallory-Weiss tear were diagnosed by endoscopy. Seventeen patients had stopped bleeding spontaneously, and 13 were actively bleeding when examined. Ten of these 13 were successfully electrocoagulated with cessation of bleeding without morbidity or mortality. Total cost and length of hospitalization were approximately one-third for those treated by electrocoagulation as compared to surgery. Endoscopic electrocoagulation of actively bleeding Mallory-Weiss tears is often successful and appears to be safe.

Adolescent↗
PubMed1979

Determination of the lower esophageal sphincter pressure in patients having a Nissen or Belsey fundoplication.

Thirty patients were studied prospectively in evaluating the Nissen (28) and Belsey (2) fundoplication manometrically using the Kronsberg probe and Honeywell recorder. Twenty-eight patients in the Nissen fundoplication group had abnormally low LESP preoperatively and normal postoperative for one year with an average increase of 9 mm. Hg. They became asymptomatic and their esophageal mucosa became normal and remained normal endoscopically for three years. The only failures were two patients treated with the Belsey fundoplication. The gas bloat syndrome occurred in two patients and was relieved by esophageal dilatation. The Nissen fundoplication should be highly recommended as the surgical procedure of choice in the treatment of reflux esophagitis not responding to medical program.

Adolescent↗
PubMed1979

Endoscopic electrocoagulation of actively bleeding arterial upper gastrointestinal lesions.

Emergency endoscopy to find the site of upper gastrointestinal bleeding is now accepted as the diagnostic method of choice. Endoscopic electrocoagulation in uncontrolled series has been successful in 98% of patients so treated (142 of 147). If a vessel is seen in an ulcer bed, some preliminary data would support surgical treatment. In my opinion, electrocoagulation is favored to prevent further bleeding. While some physicians have found electrocoagulation safe and effective, there are some who remain guardedly cautious. In the near future, a multicenter randomized study will begin to further assess the usefulness, effectiveness and safety of endoscopic electrocoagulation. Endoscopic electrocoagulation has opened a Pandora's box to exciting research in finding ways of treating acute upper gastrointestinal hemorrhage. Currently, electrocoagulation is the front runner.

Aged↗