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Biomedical subjects

J P Rat

Publications and source records attributed to J P Rat.

12 recordsLinked to original sources
PubMed1994

[Latex allergy: is the allergen thermolabile?].

The 30,000 dalton latex allergen is considered to be both hydrosoluble and thermolabile. Its thermolability does not seem to have been proved in various reviews. Three lots were prepared from an original soaking solution by different heating techniques. The prick-tests done with the three heated lots and with the original solution prove that, despite apparent contradictory results, the allergen is truly thermolabile. Could this thermolability trait be an explication for latex allergy?

Adult↗
PubMed1987

[Contact allergy from cigarette smoking].

Usually, recorded cases of allergic contact dermatitis to tobacco are confined to occupational diseases and involve agricultural workers and those engaged in manufacturing or selling the products, all of whom are in contact with tobacco leaves. We have found three cases of contact dermatitis caused by cigarette smoke, which are not occupational disease. We do not know what offending agent is, but in one case the patient is allergic to perfume and this may be the factor responsible, since she smokes only flavoured cigarettes. In addition, we need to know whether the allergen only appears during combustion and is therefore present only in cigarette smoke.

Adolescent↗
PubMed1981

[Dermatological manifestations of synovial cysts of the lower limbs (author's transl)].

Two cases of synovial cysts of the knees are reported. Thier emergeing point located far away from the joint they originate from can make the diagnosis be difficult. Puncture allows to remove synovial fluid and to inject a radio-active iodine compound to realise a cystography. The radiography of the joint demonstrates an already existing joint disease. The atypical aspects of synovial cysts are emphasized on the basis of then two cases such as pseudo-phlebitic, pseudo-arteritic, inflammatory and fistulised. The presentation of synovial cysts of the legs is frequently dermatological. The diagnosis must be suspected in order to avoid a dermatological biopsy.

Adult↗
PubMed1980

[Pemphigus foliaceus in a child. A two years follow-up under steroid. An immunosuppression therapy (author's transl)].

The observation of pemphigus foliaceus out of endemic zone in a six-year-old child is reported. The rate of anti-ICS antibodies is very high (1/6,400). The direct immunofluorescence shows the common aspect of epidermic network between the cells. Fluorescence basement membrane has been found with monospecific anti-C3 sera, and after remission with the monospecific anti-IgG sera. The clinical, histological and immunological relationship between pemphigus foliaceus in its sporadic and endemic forms and pemphigus erythematosus are discussed. The clinical and immunological regression is obtained by association of prednisone and immunodepressive therapy. After two years of treatment the maintenance dosis is not yet reached. A review of ten previous reported cases of pemphigus foliaceus in children in its sporadic form is presented.

Age Factors↗
PubMed1975

[W-shaped napkin rash in infants (author's transl)].

The W-shaped napkin rash affects mainly the convex parts of the perianal region of infants, avoiding the fold and perianal cleft. The dermatitis is of traumatic origin due to the friction of paper napkins. It heals under antiseptic treatment on condition that the use of paper napkins and rubber pants, which cause occlusion is stopped temporarily.

Anti-Infective Agents, Local↗
PubMed1975

[Penetrating hyperkeratosis of an amputated limb].

On the stump of amputated limbs, a peculiar hyperkeratotic chronic lesion may be observed. The histological picture of this lesion shows a hyperkeratotic plug perforating the epidermis. In the dermis disorganised keratine lamelles are found. This lesion could be differenciated from Kyrle's disease by the fact that it consists of a single lesion of traumatic origin and by the presence of hypertrophic bundles underlying the hyperkeratosis.

Amputation Stumps↗