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J P Tillon

Publications and source records attributed to J P Tillon.

18 recordsLinked to original sources
PubMed1994

Prevention of metritis-mastitis-agalaxia syndrome in sows.

Data collection related to farrowing performances and health parameters was performed in 20 intensive pig farms in Portugal (100-800 sows each) over 7 yr (1985-1992). At-risk profiles were obtained regarding the metritis-mastitis-agalaxia (MMA) syndrome. Using prospective surveys and subsequent preventive veterinary medicine programs in pig farms, the profile of 347 sows was analyzed by multidimensional statistical methods, and we demonstrated the value of risk-factor analysis to fight this enzootic problem. We observed a decrease in the prevalence of MMA syndrome, an increase in piglet survival and in the number of weaned piglets per sow, and a decrease in sow mortality rate. Our studies have shown the value of risk-factor analysis to fight enzootic disorders.

Animal Husbandry↗
PubMed1994

Prevention of reproductive disorders in sows.

Data collection related to production performances and health parameters was developed in 31 intensive pig farms in Portugal (from 100-800 sows each) in 1,580 of 10,000 sows over 7 yr (1985-1992). Using prospective surveys and subsequent preventive veterinary medicine programs in pig farms, we demonstrated the value of risk-factor analysis in the improvement of production performances: an increase in litter size from 9.15 piglets born/litter (sd 2.93) to 13.4 (sd 2.13); an increase in number of weaned piglets per sow per year: 15.73 (sd 1.93) to 20.46 (sd 1.92); and a decrease in returns to oestrus (25.3 to 2.3%).

Animals↗
PubMed1985

[Respiratory diseases of swine: some epidemiologic aspects].

Epidemiological surveys enable to know better the aetiology of respiratory diseases. The surveys carried out in slaughter-houses in Brittany (France) in 1980 and 1981, show a worrying situation concerning porcine respiratory diseases. Microbiological studies brought out the preponderance of the isolation of Mycoplasma hyopneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Streptococcus suis and Actinobacillus suis. Some patterns of experimental infection with Mycoplasma hyopneumoniae and Bordetella bronchiseptica are exposed.

Animals↗
PubMed1985

[Immunovirologic markers of the risk of influenza A H3N2 among swine].

A seroepidemiological survey using the radial haemolysis test has been performed on a representative sampling of the pig herds in Brittany. Since 1978, Influenza A H3N2 strains spread in that reservoir giving subclinical infections. We detected antibodies directed against the Influenza prototypes isolated during the human outbreaks from 1973 to 1977. Only one H3N2 virus was isolated in 1980: its antigenic structure was in agreement with the previous serological data. In 1984 outbreaks of swine Influenza A H3N2 occurred. The isolated viruses carried an hemagglutinin antigenically identical to the one of the 1980's strain but the neuraminidase looked clearly different. When studying the specific immune response of the young animals to the influenza infection, it appeared that the hemagglutinin of the 1984's viruses antigenically varied from the 1980's ones in about 2/3 of all the animals. With monoclonal antibodies anti N3 and N2 of the human prototypes we confirmed the data obtained in using the post infection ferret antisera. Monoclonal antibodies directed against the swine H3N2 1984 viruses are in preparation. We have no precise information so far on the mechanism of the antigenic variations.

Animals↗
PubMed1984

Diseases affecting confined sows. Data from epidemiological observations.

Having described certain aspects of confinement in modern pig reproductive farms, the writers give a list of the main diseases in sows. Urinary problems are the most frequent. They can be linked to certain aspects of confinement, as can also be locomotory or respiratory troubles. This is not sufficient, however, to condemn modern conditions in reproductive pig farms but appropriate adjustments can be made to associate good health in the animals and satisfactory performances. The advantage of studies on the behaviour of sows is stressed, notably within the framework of ecopathological studies.

Animals↗
PubMed1983

[Epizootic swine influenza on animal farms in Brittany].

Since 1976, seroepidemiological surveys using radial haemolysis and isolation trials from samples collected from pigs at the abattoir showed that Brittany was an important reservoir of swine subclinical infections due to the human Influenza A viruses H3N2. Influenza A H1Sw N1Sw subclinical infections sporadically occurred from 1979 to 1981. In January 1982 an epizootic started in Finistère which spread from west to east. The H1Sw and N1Sw antigens of 28 stains isolated from 1979 to 1982 were studied with ferret and rabbit anti sera and appeared to be variants of the previous strains (1976-1967-1961-1930). A reinforced serological survey in pigs demonstrated that both Influenza A viruses H1Sw N1Sw and H3N2 simultaneously spread in herds. There is no actual prove of recent human infections by A H1Sw N1Sw virus.

Adolescent↗
PubMed1983

Environment and gastro-enteritis.

Pathologists are always tempted to account for the occurrence of diseases by the presence or absence of some specific microbiological agent. It is the case when a major infectious agent is in contact with a receptive animal. When the Transmissible Gastro-enteritis virus is introduced into a susceptible herd, the results of the infection are calamitious. Nevertheless, the relationship between the infection and the disease is rarely simple. It is necessary to distinguish two kinds of diseases: --the monofactorial diseases (T.G.E....) --the multifactorial diseases (Colibacillosis especially after the weaning...). For these multifactorial diseases the clinical signs and the lesions are induced by an infectious agent which can be considered as a final "effector" whose multiplication depends on factors in the farm which disturb physiological or immunological mechanisms of regulation (humoral immunity, clearance, intestinal motility...). The herd system can be defined by 6 variables which could be considered as limiting factors responsible for the onset of digestive disorders: food, building, management, animal with specific and non-specific resistance, microbism and the farmer who plays a main role in the control of these variables. The disease has to be considered not only as the result of the multiplication of the microbe which is often the last actor of a morbid process but also as the disharmony of the variables defining the structure of the herd.

Animals↗
PubMed1981

Congenital tremor in pigs farrowed from sows given hog cholera virus during pregnancy.

At different stages of gestation, 3 groups of pregnant sows were inoculated with a strain of hog cholera virus (HCV). After the infection, clinical signs of hog cholera were not observed in the sows. Pigs from the sows infected on day 22 or 43 of gestation showed varying degrees of muscular tremor, ataxia, splayleg, and suckling inability. Of the pigs with tremor, 83% had cerebellar hypoplasia. Surviving pigs demonstrated persistent viral infection and continued to shed HCV, but did not have antibodies to HCV. Sows infected at 72 days of gestation farrowed numerous mummified and stillborn pigs. Signs of tremor were not seen in any pigs from these sows.

Animals↗
PubMed1980

Atypical hog cholera infection: viral isolation and clinical study of in utero transmission.

Sows in different stages of pregnancy were inoculated with a low-virulence hog cholera strain. Clinical signs of disease were not observed in the sows during pregnancy, but most of their pigs were splaylegged and had nervous disorders; perinatal mortality was high. A few pigs from sows that were inoculated during the 1st trimester of pregnancy survived and remained inapparent carriers of virus, without developing antibodies. Seemingly, these pigs were immunotolerant. Virus was transmitted from immunotolerant pigs to susceptible pigs by contact 5 weeks after farrowing, but not 3 months after farrowing, despite the persistence of the virus at a high concentration in the blood and in the organs of the immunotolerant pigs.

Animals↗
PubMed1972

[Silage of manioc roots].

Explore the source record for details and available documents.

Animal Nutritional Physiological Phenomena↗
PubMedDate not supplied

The Mycoplasma hyopneumoniae plasma membrane as a vaccine against porcine enzootic pneumonia.

From an economical standpoint, the colonization of the respiratory epithelium by Mycoplasma hyopneumoniae, the mollicute responsible for enzootic pneumonia in pigs which leads to a reduction in the weight gain/feed ratio, has serious consequences in very young animals; we show here that its is possible to efficiently protect these animals with the colostral antibodies raised in sows immunized during their gestation with M. hyopneumoniae BQ14 membranes. In an experiments using 9 sows and 75 piglets, the vaccinal preparation was found to protect 70 to 100% of the piglets (depending upon the presentation of the immunogen) as well as being totally innocuous. The best results were obtained with an adjuvant made of hydroxide aluminium gel. Of the piglets born to non-immunized sows, 8.3% exhibited typical pneumonic lesions. The vaccination procedure was found to enhance the elimination of M. hyopneumoniae from the respiratory tract of the piglets, as in 95% of the protected animals, the microorganisms could no longer be isolated. Conversely, M. hyopneumoniae was isolated from 89% of the piglets born to unvaccinated sows. A correlation was found between the protective effect and the rise in the titre of circulating antibodies directed against M. hyopneumoniae surface antigens. These results show that the plasma membrane of M. hyopneumoniae is a potential vaccine against porcine enzootic pneumonia. In particular, passively transmitted immunity via the colostrum provides the most precocious means of protection for the animals.

Animals↗