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Biomedical subjects

J P de Sigalony

Publications and source records attributed to J P de Sigalony.

7 recordsLinked to original sources
PubMed1997

Prognostic value of thoracic recurrent nerve nodal involvement in esophageal squamous cell carcinoma.

BACKGROUND: The determination of a simple and reliable prognostic factor that allows identification of patients at high risk of early cancer recurrence and subsequent death after resection of esophageal carcinoma should contribute to more accurate management of patients suffering from this disease. STUDY DESIGN: The aim of this study was to assess the prognostic value of thoracic recurrent nerve nodal involvement after curative resection of esophageal squamous cell carcinoma. The prognostic importance of gender, age, tumor penetration, and extent of lymph node involvement was evaluated in 55 patients after curative resection of esophageal squamous cell carcinoma. RESULTS: Thirty-four of 55 patients (62%) had nodal metastases and 10 of 55 (18%) had thoracic recurrent nerve nodes involved. The median overall survival was 28 months. By univariate analysis, survival was higher in association with the absence of adventitial invasion (p = 0.04), of nodal involvement (p = 0.03), and of thoracic recurrent nerve nodal involvement (p = 0.0001). In a Cox proportional hazards regression model, thoracic recurrent nerve nodal involvement appeared the strongest predictive factor (adjusted hazard ratio 8.4 (3.0-23.7)). CONCLUSIONS: Assessment of thoracic recurrent nerve nodes is appropriate to identify patients who are at high risk of disease-related death after surgical resection.

Adult↗
PubMed1995

[Imaging of hepatic tuberculoma].

We describe a case of localized macronodular tuberculosis of the liver, the so-called hepatic tuberculoma. Liver US scan demonstrated an hypoechoic well-delineated lesion of the left liver lobe. Liver CT scan demonstrated a hypodense lesion before and after contrast enhancement. Liver MR scan demonstrated a lesion hypointense to liver on T1-weighted images and isointense to liver on T2-weighted images.

Aged↗
PubMed1985

[The morphogenesis of vaginal diaphragms. New data].

The authors have studied seventeen fetuses which were stillborn as a result of late abortion or premature labour due to cervical incompetence. The authors examined the theory that suggests that the vagina is developed from the urogenital sinus and Mullerian duct. That theory holds that it is failure of canalization of the junction of the sinus and the duct that causes transverse septum formation in the vagina. According to the authors of this paper this theory does not explain how septum are formed at different places in the vagina and how it is transverse septa are not formed in the uterus. This study allows them to suggest that the vagina itself is formed by a plaque which is entirely originally from the sinus, and that it is because of a failure of this plaque to break down completely leaving behind vestigial shreds to cause these septa to appear in the vagina.

Epithelial Cells↗