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Biomedical subjects

J Padulles

Publications and source records attributed to J Padulles.

4 recordsLinked to original sources

Management of primary testicular tumors in children.

Between 1966 and 1977, 16 primary testicular tumors (PTT) were treated at the Social Security Children's Hospital in Barcelona. Treatment consisted of resection of the testis, vas deferens and spermatic vessels followed, when the peroperatory biopsy revealed malignancy, by para-aortic lymphadenectomy in 11 of the 13 patients with primary malignant testicular tumors (PMTT). Retroperitoneal radiation therapy was given to patients with positive paraaortic nodes. Chemotherapy was given to all patients with the PMTT. 77.0% of the thirteen patients with PMTT are alive from 1 to 11 yr after surgery. 81.3% of the 16 patients with 13 malignant and 3 benign tumors are alive.

Child↗

Neuroblastoma and transfer factor.

Some authors have demonstrated the cytotoxic capacity of the mother's lymphocytes against the neuroblastoma cells of the son. It is not known if that is the reason for the better prognosis of these tumors in early infancy, and it was decided to treat some similar patients with transfer factor from the mother. The conditions for the patients were: more than 2 years old, poor response to chemotherapy and/or part of the tumor not resected. 3 to 5 doses of transfer factor were administered to 3 patients 2 1/2, 4 and 6 years old. One dose was taken from 400 ml of blood and prepared as described in the literature. The patients remained without metastasis more than 1 year after the treatment.

Child↗