Biomedical subjects
J Parise
Publications and source records attributed to J Parise.
[The pediatric surgeon and injuries].
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[Congenital esophageal stenosis associated with corneosclera].
One case of congenital esophageal stenosis due to tracheobronchial remnants and associated with microphthalmos and corneosclera is reported. Diagnostic and therapeutic methods employed are discussed.
[Locoregional anesthesia in surgery with day hospitalization. Our experience with 240 cases].
Locoregional anaesthesia has become an excellent complement of conventional general anaesthesia, because it results in efficient postoperative pain relief and is easy to carry out. We have performed two types of anaesthetic blockade: of peripheral nerve (dorsal nerve of the penis and abdominogenital nerve) and caudal block. Both have been employed in pediatric day surgery with good results in postoperative pain relief and with no complications. Advantages such as early recovery of oral feeding and the normal activity of the child are possible when using these techniques of locoregional anaesthesia.
[Treatment of esophageal stenosis using pneumatic dilatation].
Esophageal stenosis secondary to lye ingestion and surgical repair of esophageal atresia have been treated traditionally with bougienage. More recently, it has been described a new technique to treat them, based in the works of GRUNTZIG which employs balloon catheters for vascular stenosis. We present a series of 11 patients treated by these method, with a total of 17 stenosis. Ten patients had ingested lye and one had an esophageal atresia. We describe the method employed. 91% of the cases had a satisfactory evolution.
Characterization of dopamine receptors on neurons grown in primary dissociated cell culture from ventral mesencephalon of mouse.
Mammalian neurons from ventral mesencephalon were grown in primary dissociated cell culture. These cultures were examined for dopamine sensitive adenylate cyclase activity and specific ligand binding of [3H]spiroperidol and [3H]flupenthixol. No stimulation of adenylate cyclase activity by 10 microM dopamine was demonstrable in cell culture homogenates. [3H]Spiroperidol bound to cell culture homogenates with high affinity and was displaced by (+)-butaclamol but not by 5-hydroxytryptamine, suggesting that the [3H]spiroperidol was bound to dopamine receptors. While [3H]flupenthixol binding was also present, it could be displaced by spiroperidol indicating that the dopamine receptor was probably of the D2 subtype. Binding of spiroperidol was proportional to the amount of cell culture homogenate, and was saturable. Are these receptors autoreceptors? The toxin 1-methyl-4-phenylpyridine (MPP+) was used to destroy dopaminergic neurons; spiroperidol binding in these cultures was found to be increased, demonstrating that most of these D2 receptors are not autoreceptors.