PubMed Health⌕ Search

Biomedical subjects

J Parizek

Publications and source records attributed to J Parizek.

6 recordsLinked to original sources
PubMed1978

Interactions between selenium compounds and those of mercury or cadmium.

Two types of mechanisms are considered in this discussion of the interactions between compounds of selenium and those of cadmium or mercury: one based on a direct chemical reaction between compounds of these elements and the other based on metabolic changes induced by selenium administration and modifying the dose-effect relationship indirectly, without a reaction between selenium and the metallic compound. The second type of metabolic changes induced by selenium may explain why an increased selenium intake provides protection not only against methylmercury but also against the toxicity of methylated selenium compounds. A better understanding of the underlying mechanisms would help in assessing the importance of these interactions for man.

Animals↗
PubMedDate not supplied

Serum selenium in adult Czechoslovak (central Bohemia) population.

The serum selenium levels in 367 healthy adult (25-64 yr) Central Bohemia residents, 176 men and 191 women, were determined using atomic absorption spectrometry. An extremely wide range of values was found in the whole population sample (< 20-296 micrograms/L) as well as in each sex or age category studied. The mean selenium concentration and 95% confidence interval calculated after logarithmic transformation of the data were 74 micrograms/L (71-77) for the whole population sample, 72 micrograms/L (67-76) for men, and 76 micrograms/L (72-81) for women. About 10% of the residents exhibited serum selenium level below 45 micrograms/L. There was no significant correlation between serum selenium and sex, age, or smoking status of participants. However, the lowest average level was found in the group of heavy smoking women: 66 micrograms/L. The selenium status of the Central Bohemia population seems to be below European average. Groups of residents having a very low nutritional selenium intake may be expected to occur in this population.

Adult↗