Biomedical subjects
Publications and source records attributed to J Parret.
The yeasts of buccal cavity were studied in a group of seventy-five subjects treated by psychotropic drugs in a psychiatric hospital, in a group of fifty-one subjects treated by psychotropic drugs at home, and in a basis group (100 + 50). It is found yeasts on 84% of treated subjects in a psychiatric hospital and only 40% in the other populations.
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Three types of sialorrhea can be distinguished: -- deglutition disorders, especially in patients with Parkinson's disease and those with anxiety, -- ptyalomania, -- primary hypersecretion at rest. Functional scintigraphic studies enable a physiological approach to be made, and this tends to group together, under the name of primary hypersecretion at rest, various clinical manifestations occurring in two main groups: -- elderly women complaining of a bitter taste in the mouth, -- plethoric men with large salivary glands. The scintigraphic recording apperances of secretion at rest, which occurs early and without obvious food stimuli, are also noted in other clinical types. It remains to be demonstrated whether they have a common physiopathological basis arising from disorders of the normal sensitivity of the buccal cavity.
Many hypotheses have been advanced to try to explain the mechanism involved in reflex secretory dysfunctions. The use of dynamic isotopic techniques and their application in clinical research enable a more precise approach to be made to assist in solving the problem. Using several examples of dysfunction of various etiologies, the authors demonstrate the existence of an excretory blocking effect from parasympathetic inhibition.
The authors describe 13 cases of hypertrophic sialosis and discuss possible mechanisms which could explain their appearance. In spite of different etiologies there is uniformity in the reactions produced. The authors therefore compared the clinical findings with those reported from animal experiments in which such lesions were artificially produced. Whether the processes of cellular hyperplasia and hypertrophy observed are related to an autonomic nervous system disorder, is open to question.
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