PubMed Health⌕ Search

Biomedical subjects

J Passas Martínez

Publications and source records attributed to J Passas Martínez.

At least 19 recordsLinked to original sources
PubMed2002

[Expression of p21ras in locally confined renal adenocarcinoma and its prognostic implications].

OBJECTIVE: The p21ras protein is encoded by the three ras genes (H-, K- and N-ras) and participate in the regulation of normal cell growth and cell differentiation. The objective of this study is to determine the expression of this protein in locally confined renal cell carcinoma, as well as its relations with different histopathological variables and their prognostic implications. METHOD: 58 renal cell carcinomas, in pT1-T3a N0 M0 (TNM 1997) stages, treated by radical or partial nephrectomy with curative intention. We analysed different clinical and anatomopathological variables, as well as expression of p21ras in paraffinated tissue, using immunohistochemical techniques. RESULTS: The mean percentage of stained nuclei was 6.1%, with a range lying between 0 and 45%. We did not obtain statistically significant association between expression of p21ras and the tumour size (p = 0.698), the nuclear grade (p = 0.676) or the histopathological stage (p = 0.095). The survival analysis also did not show significant differences when we stratified the patients using the mean value of the sample as reference point (p = 0.134). CONCLUSIONS: Expression of p21ras was not demonstrated to be related to any of the histopathological variables analysed: size, grade and stage, or with survival. Therefore, this protein does not appear to be related to the evolution of renal cell carcinoma.

Carcinoma, Renal Cell↗
PubMed2002

[Ultrasonography in urology].

After its introduction more than twenty years ago, ultrasound has continually increased in importance in urology diagnostics and is currently one of the most frequent exploratory techniques used. It corresponds to one out of every four imaging techniques carried out in medicine. The possibility of intervention under echographic control, for either diagnostic or therapeutic purposes, has been studied ever since ultrasound first appeared. Nowadays, interventionist echography is a commonly used technique in urology and is applied in a wide range of procedures carried out on the prostate gland, bladder and kidney that require echography-guided puncture techniques. Timely modifications of ultrasound for control and monitoring of treatments such as shock wave extracorporeal lithotripsy or transperineal brachitherapy has increased even more its day-to-day use by urologists. New technologies currently under development such as high-energy ultrasound in the management of kidney and prostate cancer, 3-dimensional ultrasound, Doppler-energy and contrast ultrasound have also increased the importance of this procedure in urology.

Humans↗
PubMed1996

[Non-palpable prostatic cancer. Cure with adenomectomy?].

The currently growing importance of prostate cancer (PC) is given by the large increase in the number of cases diagnosed with this condition, to a great extent due to the diffusion of the most recent diagnostic techniques. Together with the traditional rectal examination, we have available today the PSA (prostate specific antigen) and the transrectal ultrasound, which allow to diagnose tumours undetectable with palpation. This paper presents the case of a male patient with high levels of PSA (in metastatic values), normal rectal examination and three series of negative prostate biopsies in spite of a high suspicion of PC, the diagnosis being confirmed after adenomectomy, with a subsequent PSA levels normalization, these levels remaining below 3 ng/ml after 22 months follow-up, which allows to think of a "recovery" (?) with just the removal of the prostate adenoma.

Humans↗
PubMed1994

[Hydatid cyst and renal adenocarcinoma: an exceptional association].

Presentation of one case of an exceptional association in the same renal unit of a hydatid cyst and an adenocarcinoma, in a female patient who arrived to the emergency service with a picture of haematuria and lower back pain. The paper discusses the diagnostic complications posed by the large central necrotic component of the tumour, the adjacent position of both lesions and, basically, the initial intention of performing conservative surgery after it was demonstrated that the patient had mild renal insufficiency and simple cysts in the other kidney. In the end, faced with the perioperative finding of a neoplastic-like mass, radical surgery was performed. Analysis of the diagnostic and therapeutical difficulties with complex cystic masses in general.

Adenocarcinoma↗
PubMed1990

[Extracorporeal lithotripsy under echographic monitoring].

A total of 1,241 calculi corresponding to 1,000 patients were treated with the piezoelectric EDAP-LTO1 lithotriptor. All but 1% of the calculi could be localized by ultrasonic imaging. Stone localization was easily achieved in 80% and with some difficulty in 19% of the cases. All patients had a minimum follow-up of 3 months. Stone fragmentation was accomplished in 91% of pyelic, 86% of upper, 55% of mid, 90% of lower caliceal, and 37% of staghorn calculi. Fragmentation was achieved in 4 of 5 calculi in the lumbar ureter and 5 of 11 calculi in the pelvic ureter that were treated in situ. The material and method for extracorporeal shock wave lithotripsy using ultrasonic imaging are described. The advantages and disadvantages of ultrasound versus radiologic stone localization are discussed.

Evaluation Studies as Topic↗
PubMedDate not supplied

[Melanoma in urology: our experience and review of the literature].

Melanomas make up 2% of all body tumours, but the figure is increasing mainly in countries with longer sun hours daily. Genitourinary location is even more infrequent. That explains our clinical report when we discovered the three cases seen in our unit, one in a female urethra, one suprarenal and the third one in the bladder.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

[Structure of secondary or exogenous prostatic calculi].

Out of a series of 70 prostatic stones, we found 8 considered to be "secondary" or "exogenous" (i.e. originated inside the acinis, following the initial crystallization of the components of the orine introduced into the acini) which underwent crystallographic analysis, using basically the "fine plate" to determine their structure. There were found to be two types of stones: one kin essentially uric (5 in all) and others essentially oxalic (3). We observed that these may be formed by pure substances as in the case of two uric stones but generally the nucleus is made up of uric or oxalic components with a tendency in the periphery to form concentric layers of apatite or whitlockite, similar to those observed in primary or endogenous prostatic stones, accompanied by other oxalic or uric components or not. We found that both the uric acid (anhydrous) as well as the oxalates may adopt the same strucutre presented by the urinary stones (renal, vesical) but the anhydrous, uric acid may also present in the nucleus of a stone, an association of 3 structures (granuloporous + fibrosoradiated + palisaded) which does not occur in urinary stones and it may also form a structure which we call "concretioning" which has not previously been described.

Aged↗