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Biomedical subjects

J Passelecq

Publications and source records attributed to J Passelecq.

At least 37 records · Page 2Linked to original sources

[Value of radionuclide imaging for the emergency diagnosis of pulmonary embolism. 27 cases].

The urgent nature of certain cases of pulmonary ambolism limits the examinations possible to a minimum which should be rapid, immediately interpretable, absolutley harmless and of proven reliability. We reviewed 27 cases of patients referred fro possible embolectomy in a cardiovascular surgery service from 1968 to 1975. Infusion scintigraphy was carried out in all the patients and 20 underwent surgery. Retrospective study of these cases indicates that infusion lung scintigraphy confirmed the diagnosis in all 27 and indicated the need for medical or surgical treatment. The problems which were posed by certain scintigraphic images obtained using a scanning apparatus with iodine mabelled macro-agregates have disappeared with current techniques: the use of microemboli labelled with Technetium, a short-life low energy isotope, together with a scintillation camera which gives rapid AP and lateral views, the latter being essential in the determination of the topographical distribution of the defects.

Adult↗

[Enlarged heart caused by massive subepicardial lipomatosis with idiopathic dilatation of the right cavities].

The case is reported of a man of 48 with known longstanding gross cardiomegaly which was completely asymptomatic. Angiocardiography and coronary arteriography showed dilatation of the right side of the heart, and especially of the auricle. In addition, the ventricle was separated from the diphragm by a transparent non-fluid area. At operation, gross dilatation of the right atrium was confirmed, but no causative lesion could be found; there was also marked lipomatosis which involved particularly the area beneath the right ventricle. It is difficult to classify this most unusual case as either a classical dilatation of the right atrium, idiopathic or secondary, or as a cardiac lipoma or lipomatosis.

Angiocardiography↗

[Pharmacology of nitroglycerin (author's transl)].

Nitroglycerin is a vasodilating agent by virtue of its actions on vascular smooth muscle fibers. It may be administered intravenously (using either 5 p. cent dextrose, or propylene-glycol solvant), sublingually, orally or by topical administration. It is rapidly metabolized, principally by liver. Its is not toxic. The vasodilatation that is produced is both arterial and venous and is dose-related in dog (1 microgram to 100 micrograms/kg/min). However, resistance and tachphylaxis may occur. Its principal use is for angor treatment, but it has been used for the treatment of arteriopathy of the lower limbs, biliar hypertony and arterial hypertension. It has been recently administered for the treatment of acute phase of myocardial infarction and during pre, per- and post-operative periods in cardiac surgery, neurosurgery and hip surgery, as myocardial protector or anti-hypertensive agent or hypotensive agent. The absence of toxicity and the rapid reversibility of its cardio-vascular effects which are similar to the effects of sodium nitroprusside are important reasons for its use in anesthesia and cardiac intensive care.

Animals↗