On the basis of the hemocoagulation and hemostasis parameters study the actual hemostasis state was evaluated in 30 patients treated for active deep venous thrombosis (DVT) in dependence on its extent. In comparison with 30 healthy persons there were found statistically significant changes in a majority of laboratory parameters that can indicate thrombophilic state. Platelet activation, increased coagulation system activity, decreased fibrinolytic activity as well as increased fibrinogen and fibrin degradation products were demonstrated. The positive correlation between the extent of DVT and the relevance of hemostasis changes was revealed which results to these conclusions: the more extensive DVT--the more intensive tendency to thrombophilia up to intravascular blood coagulation activation was observed. Although the adequate prolongation of the prothrombin time (during the coumarin therapy) or APTT (during the heparin therapy) was achieved, the laboratory parameters showed a therapy insufficiency. In the cases of laboratory signs of the activated intravascular blood coagulation we can recommended a fortification of the oral anticoagulant therapy by its combination with antiplatelet drugs or by its temporary replacement by the heparin therapy.

Blood Coagulation↗

PubMedDate not supplied

[Changes in capillary blood flow in the gingiva during emotional excitation].

In 30 subjects aged 20 to 44 years the functional changes were studied in the gingival capillary bed, pulse rate, systolic and diastolic blood pressure before and during emotional excitation. These values compared, considerable effects were detected suggesting the general circulatory changes and substantial reduction of gingival microcirculation. This indicated that emotional stress-inducing factors may lead to periodontal diseases.

Adult↗

PubMedDate not supplied

[Changes in capillary blood flow in the gingival papillae in gingivitis].

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Adult↗