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J Peralta

Publications and source records attributed to J Peralta.

6 recordsLinked to original sources

Ambroxol plus amoxicillin in the treatment of exacerbations of chronic bronchitis.

Twenty-three patients with exacerbations of chronic bronchitis were divided in two groups in a randomized fashion receiving either amoxicillin 1500 mg/d (n = 13) or amoxicillin 1500 mg/d associated with the mucolytic drug ambroxol 90 mg/d (n = 10). The improvement in cough, expectoration difficulties and sputum purulence was statistically more evident and occurred earlier in the ambroxol + amoxicillin group than in the amoxicillin only group. Although amoxicillin plasma and sputum levels were similar in both groups, the differences in daily sputum volume, which was also statistically greater in patients receiving ambroxol, suggests that this drug favours the bronchial mucus clearance of the antibiotic which could be related to the more favourable clinical evolution. No changes were observed in lung function tests and blood gases.

Adult

Multifocal adenocarcinoma of the jejunum.

We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on microscopic examination of 14 cm of excised jejunum. Multifocal adenocarcinoma of the small intestine is extremely rare. We are not aware of any case harboring the complex changes described herein.

Adenocarcinoma

Dilatation and curettage for second-trimester abortions.

This study reports the outcome of 2,500 consecutive second-trimester abortions performed with the dilatation and curettage methods. Of the abortions, 99.2 per cent were for gestations between the fifteenth and eighteenth menstrual weeks of pregnancy. We determined that this procedure is both safer and less traumatic than intrauterine saline or prostaglandin instillation. The low incidence of uterine perforation (0.08 per cent) and over-all morbidity (2.8 per cent) and the short duration of hospitalization (average 1.1 days per patient per procedure), as well aa the absence of any death in our series, substantiate this premise.

Abortion, Induced